Home › Shoulder Pain › NCT07489937

Supraspinatus Tendon Acute Effects After Two Exercise Exposures: a Crossover Randomized Trial.

Who can join

Ages 18 to 45 · All sexes · Healthy volunteers welcome

General inclusion criteria

1. Between 18 and 45 years of age
2. Able to perform physical activity with their shoulder (moderate arm exercise for 15 min, such as tennis or housework)

General exclusion criteria

1. Shoulder fracture
2. Frozen shoulder (\>50% restriction in shoulder range of motion)
3. Shoulder surgery
4. Full rotator-cuff tears
5. Bilateral shoulder pain
6. Shoulder instability (history or positive apprehension test)
7. Corticosteroid injection in the last 6 weeks
8. Neurological diseases
9. Cardiological diseases
10. Systemic diseases (rheumatic diseases, autoimmune diseases)
11. Uncontrolled diabetes
12. Pregnancy

Group-specific inclusion criteria

1. Shoulder pain group: report unilateral shoulder pain with an average shoulder pain score of≥ 3 in the last week.
2. Control group: report no shoulder pain within 6 months.

About the study

The purpose of this study is to understand acute tendon changes after two exercise programs. We will invite individuals with and without shoulder pain to participate in this study. Every individual will participate in both exercise programs separated by up to 15 days. The researcher will evaluate the shoulder tendon using ultrasound before each exercise program and at 1 hour, 6 hours and 24 hours after each exercise program. The researcher will also evaluate self reported pain, pain sensitivity testing, and self reported questionnaires. We will compare the tendon changes after each exercise program, as well as between participants with and without shoulder pain.

What is being tested

• Isotonic exercise program (behavioral)
• Plyometric exercise program (behavioral)

Sponsor: University of Florida · Participants: 24 · Started: Apr 20, 2026

Contact the study team

• Ignacio A Raguzzi, PT · Phone: 352-665-4947

Official record on ClinicalTrials.gov — NCT07489937

Locations in the U.S.

Conditions

• Shoulder Pain

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.