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Single-Arm Study of a Treatment for Dry Eye in People Who Struggle to Wear Contact Lenses

Prospective, Single Arm Clinical Trial for the Treatment of Dry Eyes Signs and Symptoms in Patients With Limited Tolerability of Contact Lens Wear

Who can join

Ages 22 and older · All sexes

Inclusion Criteria

* \>21 years of age
* Contact lens wearer
* Previous Dry Eye Treatment
* Be on a stable dose of antihistamines/Birth Control Medication and Lifitegrast and cyclosporine.
* Schrimers Anesthetized less than or equal to 10
* CLDEQ-8 greater than or equal to 12
* Corneal Staining NEI grading scale greater than or equal to 1

Exclusion Criteria:

* Known allergy to Hyaluronic Acid
* Current topical ophthalmic drops other than dry eye treatment
* Uncontrolled Diabetes
* Diabetic Retinopathy
* Pregnancy or Lactating
* Corneal Surgery (except Refractive)
* Corneal Scars
* Keratoconus
* Ocular Herpetic Keratitis

About the study

This research study is to see if using Lacrifill is safe, easy to use, and helpful for people who wear contact lenses but can't wear them comfortably for long. Specifically, the study aims to determine whether regular use of Lacrifill over a 2-3 month period can help people wear their contacts longer without discomfort and reduce signs and symptoms of dry eye.

What is being tested

• Lacrifill (drug)

Sponsor: Vision Innovation Centers of Pennsylvania, LLC d/b/a Eye Care Specialists · Participants: 30 · Started: Dec 12, 2025

Contact the study team

• Patti Myers, COT · Phone: 5707145910
• Cheryl Bayley · Phone: 5707145915

Official record on ClinicalTrials.gov — NCT07510620

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.