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Health and Wellness Coaching to Improve Adherence to Healthy Habits and Treatment Plans in Papillary and Follicular Thyroid Cancer Survivors

Recruiting

Health and Wellness Coaching to Improve Patient Activation and Adherence to Healthy Habits in Differentiated Thyroid Cancer Care: A Mixed-Methods Pilot Study

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

* Adults ≥ 18 years
* Histologically confirmed papillary or follicular thyroid carcinoma
* Status post total thyroidectomy ± radioactive iodine therapy
* Receiving levothyroxine monotherapy (no triiodothyronine \[T3\] or desiccated thyroid products)
* Thyroid-stimulating hormone (TSH) \< 4 uIU/mL at ≥ 3 months post-thyroidectomy
* English proficiency
* Ability to provide informed consent

Exclusion Criteria:

* Medullary or anaplastic thyroid carcinoma
* Current systemic therapy for thyroid or other cancers
* Cognitive or psychiatric impairment precluding participation
* Inability to complete study procedures

About the study

This clinical trial evaluates the impact of a patient-centered health and wellness coaching (HWC) intervention on adherence to treatment plans and healthy lifestyle practices in patients with papillary or follicular thyroid cancer. Treatment for thyroid cancer often involves surgery, radioactive iodine and/or lifelong levothyroxine with regular monitoring of thyroid stimulating hormone levels. Despite strong survival rates, patients frequently report fatigue, cognitive issues, mood changes, and disruptions in daily life. Treatment burden and psychosocial strain often impair the ability to follow the treatment plan and healthy lifestyle. Studies have shown that HWC motivates patients to take ownership and accountability to perform positive and healthy behavioral changes. HWC may have a positive impact on health-related goal-setting processes and improve self-care and healthcare outcomes in certain settings. It is not yet known how HWC impacts thyroid cancer patients. Incorporating HWC into survivorship care may improve adherence to treatment plans and healthy lifestyle practices in patients with papillary or follicular thyroid cancer.

What is being tested

Sponsor: Mayo Clinic · Participants: 20 · Started: Jun 23, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07545837

Locations in the U.S.

FloridaMayo Clinic in Florida, Jacksonville

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.