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A Study Of Acute Decompensated Heart Failure

HF-FOCUS: Serial Lung Ultrasound And Peripheral Venous Pressure Monitoring To Enhance The Care Of Hospitalized Patients With Acute Decompensated Heart Failure

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Subjects ≥18 years of age
* Admitted to St. Mary's Hospital Cardiology Progressive Care Unit (Cardiology 1-5 teams)
* Admission diagnosis of either:

  1. Acute systolic heart failure
  2. Acute on chronic systolic heart failure
  3. Acute diastolic heart failure
  4. Acute on chronic diastolic heart failure
  5. Acute right heart failure
  6. Acute on chronic right heart failure
  7. Failure heart biventricular
* Able to provide informed consent and willing to undergo daily lung ultrasound examinations during their hospitalization.

Exclusion Criteria:

* Subjects \<18 years of age
* Unable to provide informed consent.
* Unwilling to undergo daily lung ultrasound examinations.

About the study

The purpose of this study is to examine shorter hospitalization length as well as a reduced rates of recurrent heart failure hospitalization compared to current standard of care in Acute Decompensated Heart Failure. A 1-day reduction in hospital length of stay in unblinded subjects receiving daily HF-FOCUS examinations compared to a blinded standard of care arm.

What is being tested

• Lung Ultrasound (diagnostic test)

Sponsor: Mayo Clinic · Participants: 500 · Started: Aug 26, 2026

Contact the study team

• Andy Dang · Phone: 507-255-7752

Official record on ClinicalTrials.gov — NCT07572955

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.