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Exploring the Feasibility of an Exercise and Noninvasive Brain Stimulation Intervention in Breast Cancer Survivors
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Breast cancer survivors (≥18 years) will be eligible to participate if the following inclusion criteria is met: * Diagnosed non-metastatic breast cancer (stages 0-3) * Completed primary breast cancer treatment (surgery, chemotherapy, radiation) for at least 3 months * Self-reported cognitive impairment after cancer treatment Exclusion Criteria: * Current participation in aerobic exercise for ≥60 min/wk * Contraindication or impairment that precludes the potential participant from exercise as defined by the American College of Sports Medicine * The presence of serious medical illnesses, metal implants, previous brain trauma, epilepsy or history of seizures, previous surgery to the head or spinal cord, or skin problems at the forehead area where the tACS electrodes will be applied * Uncontrolled cardiovascular disease * Functional impairments or physical condition that would make exercise unsafe * Metastatic cancer or diagnosis of a different cancer (excluding melanoma) within the past 5 years * Contraindication to exercise a defined by the American College of Sports Medicine
About the study
The purpose of this study is to assess the feasibility of a 4-week intervention combining exercise and transcranial alternating current stimulation (Ex+tACS) in breast cancer survivors who report experiencing cancer-related cognitive impairment. Feasibility will be assessed by measuring participant retention, adherence, satisfaction with the intervention, and safety. The researchers will also examine pre-to-post intervention changes in attention, executive function, working memory, perceived cognitive function, and physical function before, after, and four weeks post intervention completion in the Ex+tACS group compared to a control group who will receive exercise and a placebo tACS condition (CON).
What is being tested
- Exercise + transcranial alternating current stimulation (Ex+tACS) (behavioral)
- Control (behavioral)
Sponsor: Florida Atlantic University · Participants: 40 · Started: Jan 7, 2026
Contact the study team
- Ashley L Artese, PhD · Phone: 856-534-8926
Official record on ClinicalTrials.gov — NCT07587957
Locations in the U.S.
| Florida | Florida Atlantic University, Boca Raton |
Conditions
From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.