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Study of Aritinercept in Patients With Generalized Myasthenia Gravis

RecruitingPhase 1/2

A Double-Blind, Randomized, Placebo-Controlled Study to Investigate the Safety and Efficacy of Aritinercept, a Dual BAFF/APRIL Inhibitor, in Patients With Generalized Myasthenia Gravis

Who can join

Ages 18 to 85 · All sexes

Full eligibility criteria
Key Inclusion Criteria:

* Adult patients (18-85 years old)
* Myasthenia Gravis Foundation of America (MGFA) Class II-IV gMG
* Additional inclusion criteria are defined in the protocol

Key Exclusion Criteria:

* Current or medical history of malignancy within the last 5 years
* Pregnant, breastfeeding or intending to become pregnant during the Study
* Additional exclusion criteria are defined in the protocol

About the study

This clinical study will enroll patients with generalized myasthenia gravis (gMG). The goal of this clinical study is to assess the safety, tolerability, effectiveness, pharmacokinetics (how the body processes the drug) and pharmacodynamics (how the drug affects the body) of aritinercept.

What is being tested

Sponsor: Aurinia Pharmaceuticals Inc. · Participants: 81 · Started: Apr 22, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07596901

Locations in the U.S.

CaliforniaAurinia Investigational Site, Pasadena
FloridaAurinia Investigational Site, Altamonte Springs
Aurinia Investigational Site, Boca Raton
Aurinia Investigational Site, Homestead
Aurinia Investigational Site, Miami
Aurinia Investigational Site, Miami
IllinoisAurinia Investigational Site, Chicago
Aurinia Investigational Site, O'Fallon
MichiganAurinia Investigational Site, Dearborn
Aurinia Investigational Site, Flint
TexasAurinia Investigational Site, Houston

Conditions

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.