Ocular Surface Health and Tear Film Stability With a Nasal Spray Dry Eye Treatment

Inclusion Criteria:

* Is 18 years of age and has full legal capacity to volunteer (no max age requirement)
* Baseline Ocular Surface Disease Index (OSDI) \>13
* Has mild to moderate MGD
* Has best corrected visual acuity of 20/40 or better
* Has had an oculo-visual examination in the last two years
* Is willing to continue other daily dry eye management regimen (e.g., warm compresses, and/or eyelid margin cleaning)
* Is willing to discontinue other prescription medications for dry eye disease (DED) management
* Is willing to stop any topical eye drops before all planned visits
* Has read, understood, and completed the informed consent letter

Exclusion Criteria:

* Is participating in any other type of clinical or research study
* Is currently pregnant, nursing, lactating, or planning a pregnancy
* Is currently having \>50% blockage of Meibomian glands in more than two eyelids or significant atrophy (i.e., severe MGD)
* Is currently using any topical ocular medications
* Has chronic or currently active sinus related problems
* Has blepharitis \> grade 1
* Has active ocular infections
* Has a condition or in a situation which, in the examiner's opinion, may put the subject at significant risk, may confound the study results, or may significantly interfere with their participation in the study
* Has received Rx DED treatment within one week of enrollment
* Has received any thermal or light-based DED treatment within 30 days of enrollment
* Has significant corneal epithelial defects
* Has abnormal eyelid anatomy
* Has corneal neuropathic pain
* Has chronic or recurrent epistaxis (nosebleeds), coagulation disorders, or other conditions that may have led to a clinically significant increased risk of bleeding
* Has any intraocular surgery including trabeculectomy (MIGS, laser, or small incision glaucoma surgery allowed), extraocular surgery in either eye within 3 months, or refractive surgery within 12 months of enrollment
* Has a known allergy to a product used in this study