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Post-refractive IOL Outcomes With Clareon TruPlus

RecruitingObservational study

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

* Willing and able to understand and sign informed consent.
* Adult patients (\>45 years old) undergoing age-related cataract surgery that previously had myopic corneal refractive surgery.
* Dominant eye targeted for emmetropia, non-dominant eye may be targeted for ≤-0.75D (mini-monovision).
* Best monocular corrected distance visual acuity expected to be 0.1 logMAR (Snellen 20/25) or better in both eyes pre-operatively as determined by surgeon.
* Normal ocular findings aside from cataract.

Exclusion Criteria:

* Moderate-severe corneal pathology, irregular astigmatism, preexisting macular disease and other retinal degenerative diseases, diabetic retinopathy that is expected to cause future vision loss, glaucoma, severe dry eye disease, nystagmus, strabismus, zonular laxity or dehiscence, pseudoexfoliation.
* Previous history of any ocular surgery, except for myopic LASIK or PRK.
* Previous hyperopic refractive surgery.
* Corneal HOA ≥1.0 µm (RMS) with OPD at 4mm scan.
* Any active ocular infection or inflammation.

About the study

This is a prospective, single-arm, single-center, single-surgeon study evaluating the Clareon TruPlus IOL in post-refractive cataract patients. Subjects will be assessed up to 3 months post-operatively. Clinical evaluations will include refractive outcomes, visual acuity, and administration of the PRISQ Questionnaire.

What is being tested

Sponsor: Laser Defined Vision · Participants: 35 · Started: Jun 25, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07610226

Locations in the U.S.

North CarolinaPhysicians Protocol, Greensboro

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.