Evaluating the Barrier Function, Regenerative Capacity, and Soft Tissue Outcomes of Acellular Dermal Matrix

Inclusion Criteria:

* English speaking
* At least 18 years old
* Must be a patient of the UAB Dental School
* Able to read and understand informed consent document
* Patients presenting with a diagnosed need horizontal ridge augmentation with GBR without simultaneous implant placement, to allow for future dental implant placement.
* Presence of periodontally healthy, non-carious neighboring teeth and/or healthy restored dental implants on either side of the edentulous span planned for GBR, or unhealthy adjacent teeth to be extracted during the same visit.
* ≤4 mm ridge width in a Seibert Class I Edentulous span19
* No anticipated need for surgical and/or endodontic care at planned teeth adjacent to the proposed surgical site during the study period.

Exclusion Criteria:

* Non-English speaking
* Less than 18 years old
* Smokers/nicotine users (defined as currently reporting use of any form of tobacco/nicotine products)
* Patients with systemic pathologies or conditions contraindicating oral surgical procedures or adversely affecting wound healing, including:

  * Uncontrolled diabetes (HbA1c \> 7%)
  * Untreated periodontal disease
  * History of head/neck radiation
  * IV bisphosphonates
  * Immunocompromised state
  * Pregnancy
  * Acute infection at site
* Documented or suspected allergy or sensitivity to any study product