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Bio Leg: Advancing Mobility (BAM)

Adaptive Mobility Technology: A Comparative Study of C-Leg and Bio Leg

Who can join

Ages 40 to 70 · All sexes

Inclusion Criteria:

* Adults 40 to 70 years of age
* Unilateral transfemoral amputation \> 1 year
* K3 or K4 ambulator (based on the K classification system) and able to walk with no greater assistances than a single point cane
* Current microprocessor-controlled prosthesis (C-leg) user with \> 6 months experience and able to walk without a device of using a single point cane
* Able to give informed consent

Exclusion Criteria:

* Severe cardiovascular condition or other disease limiting study participation
* Skin lesions or wounds, acute or unstable fracture, diagnosis of osteoarthritis or bone impairments affecting safe participation in walking activities
* Residual limb dysfunction (i.e. joint contracture) limiting mobility or study participation
* Pain that limits walking of participation in walking activities
* Current participation in rehabilitation to address walking function

About the study

Following transfemoral amputation, regaining functional mobility, particularly the ability to navigate curbs, ramps, long distances, and the ability to stand is challenging and often unattainable. Use of advanced prosthetic limb technology can dramatically influence mobility outcomes. The purpose of this study is to compare walking function in individuals with transfemoral amputations who are current users of the C-leg (micro-processor controlled prosthetic knee; current clinical standard) to function achieved when using the Bio Leg powered micro-processor prosthetic knee.

What is being tested

• Bio Leg (device)

Sponsor: University of Florida · Participants: 12 · Started: Jun 1, 2026

Contact the study team

• Emily J Fox, PT, DPT, MHS, PhD · Phone: 904-742-2500
• Joshua C Encarnacion, BS · Phone: 904-345-8969

Official record on ClinicalTrials.gov — NCT07613502

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.