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Smart Discharges for Older Children
Smart Discharges for Older Children: A Cohort Study to Develop Prognostic Algorithms for Post-discharge Readmission and Mortality Among Children Over 5 Years of Age
Who can join
Ages 5 to 16 · All sexes
Full eligibility criteria
Inclusion Criteria: * Age between 0 and 16 years admitted to pediatric ward of hospital for proven or suspected infection * Provide informed consent * Ability to provide contact information (phone number or address) for phone or in-person follow-up Exclusion Criteria: * Child lives outside of the catchment area of a study site * Admitted for elective procedures, trauma, or short-term observation * Language barriers
About the study
This study is an observational multi-country cohort study that aims to build algorithms that can identify children between 5 and 16 years of age admitted for proven or suspected sepsis who are at risk of mortality after they are discharged in East Africa.
In low- and middle-income countries, about 5% of children discharged after hospitalization for sepsis will die in the weeks after returning home. Doctors and parents are often unaware of this period of vulnerability and are poorly equipped to identify or handle this critical situation. This project builds on past work that developed and evaluated models and the Smart Discharges program to predict, during hospitalization, an individual child's risk of recurrent illness and mortality, as well as to provide additional post-discharge support to at-risk children.
Participants will be enrolled from facilities once they are admitted, collecting clinical and social variables. They will then be followed until 6 months post-discharge to understand what happens to them after they return home. This data will be evaluated to identify which variables collected at facilities can be predictive of mortality and recurrent illness after discharge.
What is being tested
- No Intervention: Observational Cohort (other)
Sponsor: University of British Columbia · Participants: 4,000 · Started: Jan 2, 2024
Contact the study team
- Matthew Wiens, PhD · Phone: 604-829-2562
Official record on ClinicalTrials.gov — NCT07629154
Locations in the U.S.
| California | University of California, San Francisco, San Francisco (Not yet recruiting) |
| New York | Weill Cornell Medicine, Ithaca (Not yet recruiting) |
| Washington | University of Washington, Seattle (Not yet recruiting) |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.