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Prospective HemorrhoIdaL EmboliSation (PILES) Registry
Creation Of a Prospective Registry For Hemorrhoid Artery Embolization At The Joint & Vascular Institute
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Adults (≥18 years) with symptomatic bleeding internal hemorrhoids refractory to medical therapy, referred for HAE. Exclusion Criteria: * Pregnancy, coagulopathy, severe comorbidities, or inability to consent.
About the study
The goal of this observational study (prospective registry) is to collect long-term real-world data on the effectiveness and safety of hemorrhoid artery embolization (HAE) for symptomatic bleeding internal hemorrhoids in adults aged 18 years or older that have not responded to medical therapy.
The main question it aims to answer are:
1\) Does HAE lead to sustained improvement in bleeding (HDSS scores over 12-36 months?
Participants will:
* Undergo HAE as part of their routine clinical care. * Complete clinical follow-up assessments at 1, 3, 6, 12, 18, 24, and 36 months after treatment, including symptom and quality-of-life questionnaires. * Have safety outcomes tracked according to Society of Interventional Radiology guidelines.
There is no comparison group; results will be analyzed to identify predictors of success and inform best practices for patient selection and treatment.
What is being tested
- Hemorrhoid Artery Embolization (procedure)
Sponsor: Joint & Vascular Institute · Participants: 1,200 · Started: Jan 18, 2026
Contact the study team
- Layth Alkhani, BS · Phone: 847-584-3959
Official record on ClinicalTrials.gov — NCT07635784
Locations in the U.S.
| Illinois | Joint and Vascular Institute, Libertyville |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.