Home › Stroke › NCT07643337
Impact of VNS With Rehab on Gait Post-Stroke
Recruiting
The Impact of Vagus Nerve Stimulation Paired With Rehabilitation on Lower Limb and Gait Functions After Ischemic Stroke
Who can join
Ages 22 to 80 · All sexes
Full eligibility criteria
Inclusion Criteria: * Approved for Vagus Nerve Stimulation (VNS) and rehabilitation therapy * ≥22 years and ≤ 80 years * Only patients who elect to undergo VNS therapy for stroke-related upper limb deficits * Residual active movement in the affected limb's thumb and other 2 fingers * Stroke-related deficits in the lower limbs and gait with a Functional Ambulation Category (FAC) ≥3 * Able to follow simple instructions and independently walk short distances with or without external support or leg orthoses, but without manual contact with another person Exclusion Criteria: * Intact lower limb functions (Fugl-Meyer score=34) * Not a candidate for VNS therapy according to FDA guidelines * Pregnant patients
About the study
This is a prospective, double-blinded, randomized controlled study to evaluate the impact of Vagus Nerve Stimulation (VNS) therapy on lower limb function.
What is being tested
- Vagus Nerve Stimulation Therapy (device)
Sponsor: State University of New York at Buffalo · Participants: 24 · Started: 2026-06
Contact the study team
- Ellen M Carl, PhD, CCRP · Phone: 716-218-1000
- Amylynn M Liskiewicz, MA, CCRP · Phone: 716-218-1000
Official record on ClinicalTrials.gov — NCT07643337
Locations in the U.S.
| New York | University at Buffalo Neurosurgery, Buffalo |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.