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Mako-MORE Registry

RecruitingObservational study

A Prospective, Multi-center, Post-market, Registry-based Evaluation of the Clinical Outcomes in Patients Receiving a Stryker Implant With Use of the Mako Robotic-Arm Assisted System (Mako-MORE)

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

* The subject is skeletally mature, and ≥ 18 years old.
* The Subject has signed and dated an IRB/EC approved, study specific Informed Patient Consent Form (ICF).
* The subject is scheduled to undergo manual arthroplasty or Mako Robotic-Arm Assisted Arthroplasty according to IFU.
* The subject is willing and able to comply with postoperative scheduled clinical evaluations.

Exclusion Criteria:

* The subject is not able to express his/her consent as deemed by the investigator.
* The subject is not able to fulfill a self-assessment questionnaire or follow-up visits as deemed by the investigator.
* The subject is a prisoner.
* Per surgeon discretion the subject is not a candidate for the study.
* The subject is pregnant or breastfeeding.

About the study

This is a prospective, post-market, multi-center, registry-based observational study designed to collect real-world clinical data on patients undergoing joint arthroplasty with Stryker implants, with or without the use of the Mako Robotic-Arm Assisted System. The registry will collect prospective data on patient characteristics, procedural details, patient-reported outcomes, radiographic assessments, and adverse events. Patients will be enrolled into procedure-specific cohorts and followed for up to five years postoperatively.

What is being tested

Sponsor: Stryker Orthopaedics · Participants: 950 · Started: Jul 13, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07647354

Locations in the U.S.

FloridaMayo Clinic (Jacksonville), Jacksonville (Not yet recruiting)
KentuckyUofL Health, Louisville
New YorkNYU Langone Orthopedic Hospital, New York
OhioCleveland Clinic, Cleveland (Not yet recruiting)
Rhode IslandRobotic Joint Replacement Institute - Ortho Rhode Island, Wakefield (Not yet recruiting)

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.