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INtegrating Systematic PatIent-Reported Evaluations in Multi-Disciplinary Tumor Boards: The INSPIRE Study

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Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion/Exclusion Criteria: We will include two populations: (1) patients and (2) clinical team members involved in the MDTB.

Inclusion Criteria:

* Inclusions Criteria- Patients:

  1. aged 18 years or older;
  2. with suspected or confirmed diagnosis of pancreatic, breast, and gynecologic cancer (all stages) within 8 weeks of diagnosis. This may include diagnosis of a new recurrence. Patients may have had some treatment prior to being seen at a participating institution as long as they are within the 8-week timeframe. Patients may be diagnosed at a participating institution or outside. If there is diagnostic uncertainty and/or patient has not received treatment they will be allowed to participate if they are beyond the 8 weeks of diagnosis.
  3. intention to be treated at a participating institution;
  4. with verbal fluency in English or Spanish; and
  5. scheduled to be discussed at MDTB.
* Inclusion criteria - Clinicians:

All clinical team members participating in the pancreatic, breast, or gynecologic MDTB at a participating site will be included and have pre-emptively agreed to participation.

Exclusion Criteria:

* Exclusion criteria - Patients:

Individuals with plans to receive cancer treatment outside the participating institution and inability to speak English or Spanish.

* Exclusion criteria - Clinician:

Clinicians will retain the opportunity to opt-out of participation, in which case their portions of the discussion will not be included in the analysis; however, this is not anticipated based on pilot data.

About the study

The purpose of the study is to characterize baseline multidisciplinary tumor board (MDTB) context and variability, evaluate the relationship between baseline fitness of patients with cancer and initial treatment recommendations, and assess the impact of the INSPIRE intervention, which involves including electronic patient reported outcomes (ePROs) within MDTB on MDTB discussion content, provider burden, treatment recommended and received, healthcare utilization, and patient-reported outcomes.

What is being tested

Sponsor: University of Alabama at Birmingham · Participants: 2,748 · Started: Oct 2, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07671937

Locations in the U.S.

AlabamaUniversity of Alabama at Birmingham, Birmingham
CaliforniaUniversity of California Los Angeles (UCLA), Los Angeles (Not yet recruiting)
OklahomaUniversity of Oklahoma (OU) Health Campus, Oklahoma City (Not yet recruiting)

Conditions

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.