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Period Pills for Menstrual Regulation: A New Reproductive Health Option

RecruitingPhase 4Healthy volunteers welcome

Who can join

Ages 18 and older · Women · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* Be 18 years old or older
* Read and speak English
* Know the date of their last menstrual period within 2 days
* Have a period that is late by up to 21 days
* Must have had regular periods in the last 4 months
* Does not want to be pregnant
* Does not want to verify pregnancy status
* Understand that if they are pregnant, the pills will end their pregnancy
* Does not have contraindications to mifepristone and misoprostol (Risk factors for ectopic pregnancy; history of bleeding disorder or anticoagulant therapy; history of chronic adrenal failure, long-term corticosteroid therapy; allergy to mifepristone/misoprostol/prostaglandins; history of hemorrhagic disorders or anticoagulant therapy; history of inherited porphyrias; has an IUD; currently use a contraceptive implant or injectable)

Exclusion Criteria:

* Under 18 years old
* Does not read and speak English
* Does not know the date of their last menstrual period within 2 days
* Has not had regular periods in the last 4 months
* Wants to be pregnant
* Wants to verify pregnancy status
* Does not display understanding that if they are pregnant, the pills will end their pregnancy
* Has any contraindications to mifepristone and misoprostol (Risk factors for ectopic pregnancy; history of bleeding disorder or anticoagulant therapy; history of chronic adrenal failure, long-term corticosteroid therapy; allergy to mifepristone/misoprostol/prostaglandins; history of hemorrhagic disorders or anticoagulant therapy; history of inherited porphyrias; has an IUD; currently use a contraceptive implant or injectable)

About the study

The Period Pills Study is a prospective observational study among people who decide to use a combination of mifepristone and misoprostol for menstrual regulation.

What is being tested

Sponsor: University of California, San Francisco · Participants: 100 · Started: Jun 22, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07671989

Locations in the U.S.

VirginiaRoanoke Health Center, Roanoke

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.