The Abuse Liability of IQOS Heated Tobacco Products Among Adults Who Smoke

Inclusion Criteria:

* Adults 21-65 years
* Adults who smoke (defined as ≥ 5 days weekly use of either menthol or non-menthol cigarettes over the past 3 months)
* Willing to provide informed consent and abstain from using nicotine products 12 hours before each visit
* Willing to bring UBC to each study visit
* Read, write and speak English

Exclusion Criteria:

* Current use of other non-combustible nicotine products (e.g., electronic \[e\]-cigarettes, HTPs; \[defined as ≥ 5 days weekly use in the past 30 days\])
* Planning to quit nicotine use and/or use of any smoking cessation medication in the past 30 days
* Current diagnosis of any lung diseases (e.g., asthma, cystic fibrosis, or chronic obstructive pulmonary disease)
* Self-reported unstable or significant psychiatric conditions (past/stable conditions will be allowed)
* History of cardiac event or distress within the past 3 months
* Deaf, hard of hearing, or have a severe motor disability
* Are currently pregnant, planning to become pregnant, or breastfeeding (urine pregnancy test will be completed at each visit throughout the study)