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Comparison of Two Quantitative EMG Monitors for Deep Neuromuscular Block in Laparoscopic/Robotic and VATS Surgery

Comparison of Two Quantitative Electromyography Monitors for Deep Neuro Muscular Block in Patients Undergoing Abdominal Laparoscopic/Robotic or Thoracic Video-Assisted (VATS) Surgeries

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* Adult male or female patients aged ≥ 18 years old.
* Patients undergo elective abdominal laparoscopic/robotic or thoracic video-assisted (VAT) surgeries requiring general anesthesia for greater than 3 hours at The Ohio State University Wexner Medical Center.
* Able to provide a signed, written informed consent.
* Able to speak, read, and write in English.
* ASA physical status I-III.

Exclusion Criteria:

* Patients who require emergency surgery or an emergent intervention.
* Any documented cognitive or psychological disorders that, in the investigator's opinion, can interfere with the patient's pain perception.
* Vulnerable populations: pregnant females, prisoners, breastfeeding.
* Presence of any medical condition that, in the opinion of the principal investigator, should exclude the patient from the study (patients with pre-existing neuromuscular diseases.
* Allergy or contraindications to any of the anesthetics, NMB agents, or sugammadex.
* Patients with anatomical abnormalities of the hands or arms that prevent proper placement of the sensors for nerve stimulation.
* Limited access to the monitoring area due to surgical positioning.
* Patients with peripheral vascular disease, since it may affect measurement accuracy.

About the study

The main objective of the study is to compare the frequency of intraoperative spontaneous diaphragmatic movements and breath-initiation efforts in participants undergoing robotic and/or thoracic surgery under deep neuromuscular blockade (NMB), using either the TetraGraph or TwitchView applied to the dominant hand. These events will serve as objective indicators to evaluate each device's ability to monitor and maintain adequate deep NMB.

What is being tested

• TetraGraph (Senzime)-Guided Neuromuscular Monitoring (Dominant Hand) (device)
• TwitchView (Blink)-Guided Neuromuscular Monitoring (Dominant Hand) (device)

Sponsor: Ohio State University · Participants: 35 · Started: Feb 9, 2026

Contact the study team

• Alberto Uribe, MD · Phone: 6142933559
• Elvia Vera, MD · Phone: 6142933559

Official record on ClinicalTrials.gov — NCT07706504

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.