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Improving Care Delivery for Patients With Mental Illness and Cancer Across a Cancer Center Network

Improving Care Delivery for Individuals With Mental Illness and Cancer Across a Cancer Center Network: A Randomized Trial

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

1. be ≥18 years
2. have a prior diagnosis of SMI, defined as schizophrenia spectrum disorder, bipolar disorder, or major depressive disorder with previous psychiatric hospitalization
3. have a new primary diagnosis of invasive breast, head/neck, gastrointestinal (GI), genitourinary (GU), thoracic, or gynecological cancers that can be treated with curative intent
4. be within 8 weeks of initial oncology consultation at or referral to a community cancer affiliate site of the Mass General Brigham Cancer Institute at MGH
5. be able to read and write in English, Spanish, or Portuguese

Exclusion Criteria:

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About the study

The proposed project is an implementation-effectiveness randomized trial of a person-centered collaborative care model for patients with serious mental illness and new cancer. The BRIDGE NET intervention is theoretically informed, pragmatic, and delivered virtually by an interdisciplinary team and includes early psychiatry consultation, integrated oncology and mental health treatment planning and regular patient outreach to adddress barriers to care. The BRIDGE NET intervention addresses the unique needs of patients with mental illness and cancer. To increase the reach of specialty cancer and mental health care, there is a critical need for interventions that can be delivered virtually. This work has can inform the standard of care for patients with serious mental illness and cancer and lay the groundwork for future multi--site trials.

What is being tested

• BRIDGE NET (other)

Sponsor: Massachusetts General Hospital · Participants: 248 · Started: Oct 20, 2026

Contact the study team

• Kelly Irwin, MD, MPH · Phone: 617-726-2000

Official record on ClinicalTrials.gov — NCT07707362

Locations in the U.S.

Conditions

• Cancer (all types)

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.