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FlexED: Full Threshold ED Substudy

FlexED: A Digital Gamified Early Intervention for Eating Disorders

Who can join

Ages 15 to 25 · All sexes

Inclusion Criteria:

* Female age 15-25 years
* Weight Concerns Scale score of \>=47
* Meets diagnostic criteria for an eating disorder based on the DSM-5

Exclusion Criteria:

* Psychosis, substance use disorder, or current suicidal ideation or self-harm
* Start or change in psychiatric medications within the past month
* Non-English speaking

About the study

The purpose of this study is to test whether a new digital intervention decreases eating disorder symptoms in young women with eating disorders by changing how they experience thoughts and feelings about their body. The digital intervention is based on Acceptance and Commitment Therapy (ACT). Participants complete up to 7 digital intervention sessions using their mobile phone that include a character, story line and interactive exercises, games and digital rewards.

Researchers will examine the impact of the intervention on participants' ability to respond flexibly to body-image distress or triggers, measuring things like heart rate, eye movements, and reaction time to body-image related words and images, and examine changes in eating disorder symptoms before and after intervention.

What is being tested

• FlexED (behavioral)

Sponsor: Duke University · Participants: 6 · Started: Sep 1, 2026

Contact the study team

• Rhonda Merwin, PhD · Phone: 919-681-7231

Official record on ClinicalTrials.gov — NCT07732829

Locations in the U.S.

Conditions

• Eating Disorders

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.