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Using Personalized Rehabilitation to Reduce Disease and Increase Activity of Patients With Polymyalgia Rheumatica

Using Personalized Rehabilitation to Reduce Disease and Increase Activity of Patients With Polymyalgia Rheumatica: a Feasibility Randomized Clinical Trial

Who can join

Ages 50 and older · All sexes

Inclusion Criteria:

* Patient reports pain \> 3 (0-10, 0 = no pain; 10 = worst pain imaginable)
* Diagnosis or flare of PMR according to the European League against Rheumatism/American College of Rheumatology (EULAR/ACR) classification criteria as follows (must satisfy all criteria)10:

  * Age ≥50 years at time of diagnosis
  * Presence of bilateral shoulder pain
  * Elevated acute phase reactants C-reactive protein (CRP) \>10 milligram/Liter and/or Erythrocyte Sedimentation Rate (ESR) \>30 millimeters/hour\*
  * A score ≥4 at the time of diagnosis based on the following (without ultrasound):

    * Duration of morning stiffness \>45 minutes: 2 points
    * Hip pain or limited range of motion: 1 point
    * Seronegative for rheumatoid factor and anti-cyclic citrullinated peptide: 2 points
    * Absence of other joint involvement: 1 point
* Able to give informed consent
* Physician's clearance to participate in physical activity

Exclusion Criteria:

* Diagnosis of fibromyalgia, neuropathic muscular disease, complex regional pain syndrome, or small fiber neuropathy
* planned major surgical procedure during the study
* Current active uncontrolled infection

About the study

Polymyalgia rheumatica (PMR) is a condition that causes joint pain and stiffness, making it hard for people to do everyday tasks. Movement pattern training is a special, personalized rehabilitation program that aims to reduce pain by improving how people move during their daily activities. The investigators plan to test if it's possible to conduct a detailed study to find out how effective Movement pattern training is for people with PMR. The investigators will look at whether it helps them perform activities they want to do, reduce their use of certain medications, and strengthen their muscles. The investigators will also gather feedback from patients about their experience with Movement pattern training. This study will help us understand if carrying out a larger study on Movement pattern training's effectiveness is practical.

What is being tested

• Movement Pattern Training (MoveTrain) (behavioral)
• Usual Care (other)

Sponsor: Washington University School of Medicine · Participants: 20 · Started: Aug 15, 2026

Contact the study team

• Marcie Harris-Hayes, DPT, MSCI · Phone: 314-286-1435

Official record on ClinicalTrials.gov — NCT07749547

Locations in the U.S.

Conditions

• Polymyalgia Rheumatica

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.