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A Study to Evaluate the Metabolism, the Routes and Extent of Elimination, and Drug Levels of [14C]Navlimetostat (BMS-986504) in Healthy Female Participants
RecruitingPhase 1Healthy volunteers welcome
A Phase 1 Study to Evaluate the Mass Balance, Metabolism, Excretion, and Pharmacokinetics of [14C]Navlimetostat (BMS-986504) at Steady State in Healthy Female Participants
Who can join
Ages 18 to 55 · Women · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria * Participants must have a body mass index (BMI) of 18.0 to 35.0 kg/m2, inclusive. * Participants must have a recent history (ie, last month) of a minimum of 1 bowel movement per 2 days. * Participants must be female (as assigned at birth) who is an individual not of childbearing potential (INOCBP), defined as one of the following:. i) Surgically sterile (eg, hysterectomy, bilateral oophorectomy, or bilateral salpingectomy). ii) Postmenopausal, defined as ≥ 12 consecutive months of amenorrhea in an individual over the age of 45 years (no other biological or physiological causes), and individuals \< 55 years of age with 12 months of amenorrhea must have serum FSH levels \> 40 mIU/mL at screening to confirm menopausal status. Exclusion Criteria * Participants must not have any significant acute or chronic medical illness. * Participants must not have current or recent gastrointestinal disease. * Participants must not have a history of prolonged bleeding or excessive bruising. * Other protocol-defined Inclusion/Exclusion criteria apply.
About the study
The purpose of this study is to evaluate the metabolism, the routes and extent of elimination, and drug levels of \[14C\]Navlimetostat (BMS-986504) in healthy female participants
What is being tested
- Navlimetostat (drug)
- [14C]Navlimetostat (drug)
Sponsor: Bristol-Myers Squibb · Participants: 6 · Started: Sep 29, 2026
Contact the study team
- BMS Clinical Trials Contact Center www.BMSClinicalTrials.com · Phone: 855-907-3286
Official record on ClinicalTrials.gov — NCT07777133
Locations in the U.S.
| Wisconsin | Local Institution - 0002, Madison (Not yet recruiting) |
From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.