Knee Cartilage Repair Registry

Inclusion Criteria:

Prospective Subjects

* Provides written informed consent.
* Is eighteen (18) years of age or older at time of consent and considered skeletally mature in the opinion of the investigator.
* Scheduled to undergo knee cartilage surgery with the Marketed Product-MP01 OR other knee cartilage repair surgery.
* For subjects having other knee cartilage repair surgery:

  \- Falls within Marketed Product-MP01 on label indication: Knee chondral or osteochondral lesions (ICRS grade III and above, 1-7cm2) in patients with or without mild-moderate knee osteoarthritis (K/L 0-3).
* Has an electronic device and is willing and able to use the device to complete the 'Electronic Clinical Outcomes Assessment' (eCOA).
* Willing and able to complete all requested questionnaires.
* Able to follow instructions and deemed capable of completing registry protocol requirements.

Retrospective/Prospective Subjects

* Provides written informed consent.
* Was eighteen (18) years of age or older at time of surgery and considered skeletally mature at that time in the opinion of the investigator.
* Underwent knee cartilage repair surgery with the Marketed Product-MP01 within the last 2-years.
* Has an electronic device and is willing and able to use the device to complete the eCOA.
* Willing and able to complete all requested questionnaires.
* Able to follow instructions and deemed capable of completing registry protocol requirements.
* Consents to retrospective data being collected from pre-operative visit(s) and surgery through to the point of consent as available in their medical notes.

Exclusion Criteria:

* History of allergic reaction or intolerance of materials containing calcium carbonate or hyaluronate/coral derivatives.
* Is actively participating in a cartilage repair clinical trial.
* For subjects having other knee cartilage repair surgery:

  \- Treatment will be on patellar lesion(s).
* Has participated previously in this registry (with the index or contralateral knee).
* Meets the definition of a Vulnerable Subject per ISO 14155 Section 3.56.