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Transitional Intervention for Hyperacusis in Autism
Effectiveness of an Individualized Progressive Treatment for Expanding Sound Tolerance in Adults With Autism Spectrum Disorder: A Crossover Randomized Controlled Trial (RCT)
Who can join
Ages 18 to 39 · All sexes
Full eligibility criteria
Inclusion Criteria * Adults age 18 to 39 years * Autism spectrum disorder * Mild-to-severe loudness hyperacusis indicated by a score ≥ 22 on the Hyperacusis Questionnaire (HQ) and LDLs for tones ≤ 80 dB HL at two or more audiometric frequencies in at least one ear. * No more than slight or mild sensorineural hearing loss from 250 to 8000 Hz * Normal tympanograms consistent with normal middle ear function * Normal "tone" decay response for "comfortable but soft" broadband noise * Ability understand informed consent in English * Availability and willingness to conform to the study visit schedule * Diagnosis of autism (including Asperger's and other diagnoses "on the spectrum") * Ritvo Autism Asperger Diagnostic Scale-Revised (RAADS-R) score of 65 or greater to confirm ASD diagnosis * Full-Scale IQ score of 90 or greater on the Weschler Abbreviated Scale of Intelligence (WASI-II; 2-lists). Exclusion Criteria * Management for head trauma within the past 6 months * Management for traumatic brain injury within the past 6 months * Management for epilepsy within the past 6 months * Management for seizures within the past 6 months * Management for or other neurological disorders within the past 6 months * Otologic surgical procedures within the past 6 months * Actively fluctuating hearing loss within the past 6 months * Acute Meniere's disease within the past 6 months * Labyrinthitis within the past 6 months * Conductive hearing loss * Otalgia * Ongoing use of ototoxic medications. * Active or past drug or alcohol dependent histories * Known scheduling or travel conflicts
About the study
The main goal of this clinical trial is to evaluate the effectiveness, benefits, and post-treatment persistence of an intervention for loudness hyperacusis in adults with autism spectrum disorder (ASD). The main questions it aims to answer are:
* Does the intervention increase loudness tolerance * Does the intervention reduce symptoms related to loudness hyperacusis Researchers will compare measures related to loudness hyperacusis before, during, and after the intervention.
Participants will:
* Be randomly assigned to either one of two groups. One group will receiver the intervention immediately. This group will be evaluated during the 6-month intervention and evaluated for 6 months after the end of the intervention. The other group will be evaluated for 6 months before the intervention and during the 6-month intervention. * Visit the test site once every month over the course of a year for evaluation and intervention activities * Keep a diary of their symptoms and the number of hours per day they engage in the intervention
What is being tested
- Transitional Intervention for Hyperacusis in Autism (other)
Sponsor: University of Central Florida · Participants: 40 · Started: 2026-08
Contact the study team
- David A. Eddins, Ph.D. · Phone: 407-823-0811
- Kelly N. Jahn, Ph.D. · Phone: 972-883-2358
Official record on ClinicalTrials.gov — NCT07798297
Locations in the U.S.
| Florida | Communication Technologies Research Center, Orlando (Not yet recruiting) |
| Texas | Callier Center for Communication Disorders, Dallas |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.