Home › Diarrhea › NCT07818902

Rural Water Filtration and Health Study

Expanding Safe Water Access to Improve Health Outcomes in Appalachia: The Rural Water Filtration and Health (RWELL) Trial

Who can join

6 Months · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* Home is located in a study county in southwest Virginia or northeast Tennessee
* There is at least one adult (aged 18 or older) who regularly (\>6 months per year) resides in the household
* Household does not have utility-supplied water (and \<33% of household members regularly drink bottled water)
* Reported household income is \<80% of the county median income (based on US Department of Housing and Urban Development thresholds by household population)

Exclusion Criteria:

* None (no exclusion criterion based on gender, race, ethnicity, language, or literacy)

About the study

The goal of this intervention trial is to learn if the use of drinking water filters will result in improved health outcomes for people living in homes with well water and spring water in rural regions of Central Appalachia.

What is being tested

• Water filter (device)

Sponsor: Virginia Polytechnic Institute and State University · Participants: 1,584 · Started: 2026-11

Contact the study team

• Kelsey Lane Warmbrod, PhD · Phone: 540-231-1816
• Bethesda O'Connell, DrPH · Phone: 423-439-4816

Official record on ClinicalTrials.gov — NCT07818902

Locations in the U.S.

Conditions

• Diarrhea

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.