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Short-term Spinal Stimulation Effects in Cerebral Palsy

Recruiting

Acute Effects of Transcutaneous Spinal Stimulation on Spasticity and Gait in Cerebral Palsy

Who can join

Ages 4 to 65 · All sexes

Full eligibility criteria
Inclusion Criteria:

Individuals who:

* have a diagnosis of spastic cerebral palsy or high likelihood of CP diagnosis
* are 4-65 years of age
* have spasticity in lower-extremity muscles
* are at a functional Gross Motor Function Classification System (GMFCS) Level I-III
* can walk for at least 10 minutes with/without support
* can understand and follow simple directions
* have a stable medical condition, as reported by the caregiver/parent

Exclusion Criteria:

Individuals who:

* who have had lower-extremity surgery or injury in the prior 12 months
* have had botulinum toxin injections in the prior 3 months
* have had selective dorsal rhizotomy (SDR) in the past
* have uncontrolled seizures
* have significant cardiovascular or musculoskeletal disease that would prevent full participation
* are dependent on ventilation support
* have implanted stimulator (e.g. epidural stimulator, vagus nerve stimulator, pacemaker, cochlear implant, etc) or drug delivery device (e.g. baclofen pump)
* have established osteoporosis and taking medication for osteoporosis treatment.
* have rheumatic diseases (rheumatoid arthritis, systemic lupus erythematosus, etc.)
* have active cancer
* have received stem cell injections into the spinal cord

About the study

This research study will examine the acute effects of non-invasive spinal stimulation on spasticity and walking in individuals with cerebral palsy. The hypothesis is that walking with spinal stimulation will lead to greater reductions in spasticity than walking without spinal stimulation. Additionally, it is hypothesized that the average step length and Gait Deviation Index will be higher while walking with spinal stimulation compared to walking without spinal stimulation.

What is being tested

Sponsor: University of Washington · Participants: 20 · Started: Aug 13, 2026

Contact the study team

Official record on ClinicalTrials.gov — NCT07826494

Locations in the U.S.

WashingtonUniversity of Washington, Seattle

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.