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The Parasite and Infestation Study

Understanding the Experience of Patient-Physician Diagnostic Incongruency: I Know Something is Wrong But No One Believes Me

Who can join

Ages 18 to 70 · All sexes

Inclusion Criteria:

* Men and women aged 18-70 years old
* At least 50% certain that they have an active infection/infestation/parasite, despite being told by doctor that they do not
* Ability to read and speak English
* Access to a computer or phone for virtual visit
* No self-reported history of schizophrenia-spectrum disorder

Exclusion Criteria:

* Active substance use disorder (excluding nicotine and caffeine)
* History of severe head trauma
* Current use of antipsychotics
* Serious medical or neurological illness known to interfere with cognitive functioning
* Diagnosis of a learning disability or cognitive disorder

About the study

Many people have evidence of bugs, parasites, and infestation, but are told by others that they cannot find a cause. This distressing and frustrating experience can last for years, as the person seeks answers. The current study aims to understand the experience of these individuals. In a 1-2 hour session over Zoom, the investigators will ask participants questions about their experience, have them complete self-report questionnaires, and ask them to complete a few games on the computer. The investigators' goal is to help characterize and understand individuals with this experience to aid in better treatment and inform recommendations for providers.

What is being tested

• No intervention - observational study (other)

Sponsor: Vanderbilt University Medical Center · Participants: 25 · Started: Dec 31, 2024

Contact the study team

• Sheffield Lab · Phone: (615) 686-2488

Official record on ClinicalTrials.gov — NCT07849907

Locations in the U.S.

Conditions

• Parasitic Diseases

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.