Satavari and Ashoka for Menopause (SAM) Study

Inclusion Criteria:

* Females aged 40-65 years.
* Postmenopausal women in good overall health and fulfilling menopausal criteria set at the MRS score more than 5.
* Subjects had experienced absence of regular menstrual cycle for at least 3 months.
* Willingness to sign consent, follow protocols and regimen intake, as well as maintain normal physical activity and follow study procedures.

Exclusion Criteria:

* Not on Hormone Replacement Therapy (HRT) or had discontinued HRT at least 12 months before admission to the study.
* History of breast cancer,
* BMI ≥ 40mg/kg².
* Prior removal of both ovaries.
* Pregnancy, breastfeeding, or plans for pregnancy.
* History of breast or uterine cancer, including hyperplasia, endometrial carcinoma, or cervical neoplasia.
* Unstable medical conditions or clinically diagnosed depression requiring treatment.
* Self-reported drug or alcohol abuse.
* Allergy or sensitivity to herbal ingredients.
* Undiagnosed abnormal vaginal bleeding;
* A bilateral hysterectomy;
* History of chronic alcoholism,
* Medication hypersensitivity, or allergy to dietary supplement ingredients;
* Acute systemic infection or abnormal laboratory values.
* No antibiotics use in past 30 days.
* No regular probiotics use in past 30 days.