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Monitored Anesthesia Care and Soft Tissue Infiltration With Local Anesthesia Feasibility Trial

Recruiting

Monitored Anesthesia Care and Soft Tissue Infiltration With Local Anesthesia for Older Adults With Hip Fracture: A Multi-Center Feasibility Randomized Clinical Trial

Who can join

Ages 65 and older · All sexes

Full eligibility criteria

Inclusion Criteria:

\- Adults aged 65 years and older undergoing surgical repair for an intertrochanteric or femoral neck hip fracture are eligible for the study. Fracture fixation can be with cannulated screws, a sliding hip screw (or similar device), a short cephalomedullary nail, or a long cephalomedullary nail.

Exclusion Criteria:

* Patients with pre-operative delirium;
* Patients with a periprosthetic or peri implant fracture;
* Patients at risk for malignant hyperthermia (history of malignant hyperthermia, family history of malignant hyperthermia susceptibility, history of rhabdomyolysis);
* Patients with contraindication to local anesthesia;
* considered unsuitable for randomization by the surgeon or anesthesiologist on the basis of the physician's clinical assessment (e.g. severe pulmonary disease);
* treated with hip arthroplasty
* received a preoperative peripheral nerve block; or
* severe dementia defined as pre-operative MMSE score \< 15.

About the study

The purpose of this study is to establish preliminary efficacy of Monitored Anesthesia Care and Soft Tissue Infiltration with Local Anesthesia (MAC-STILA) on severity of post operative delirium and secondary outcomes in patients with and without cognitive impairment.

What is being tested

Monitored Anesthesia Care (MAC) (procedure)
Soft Tissue Infiltration with Local Anesthetic (STILA) (procedure)
General Anesthesia (procedure)

Sponsor: NYU Langone Health · Participants: 140 · Started: Oct 27, 2026

Contact the study team

Shifa Ahmed · Phone: 774-217-2467

Official record on ClinicalTrials.gov — NCT07897656

Locations in the U.S.

Illinois	Northshore (Endeavor Health), Evanston (Not yet recruiting)
Maryland	Johns Hopkins University, Baltimore (Not yet recruiting)
New York	NYU Langone Health, New York Jamaica Hospital, Queens (Not yet recruiting)
Utah	University of Utah, Salt Lake City (Not yet recruiting)

Conditions

Hip Injuries and Disorders

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.