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Maximum Lysis on Thromboelastography as a Marker of Systemic Severity in Acute Allergic Reactions

Who can join

Ages 12 and older · All sexes

Inclusion Criteria:

* Age 12 years or older.
* Presentation to the emergency department with suspected allergic reaction, anaphylaxis, or angioedema based on chief concern.
* Ability to obtain thromboelastography during the acute presentation.

Exclusion Criteria:

* Known inherited coagulation or fibrinolytic disorders.
* Active major bleeding at presentation.
* Receipt of thrombolytic therapy.
* Inability to obtain thromboelastography promptly.

About the study

The purpose of this research is to better understand the mechanisms behind allergic reactions.

What is being tested

• Thromboelastogram (diagnostic test)

Sponsor: Mayo Clinic · Participants: 250 · Started: Oct 23, 2026

Contact the study team

• Study Coordinator · Phone: 507-255-5056

Official record on ClinicalTrials.gov — NCT07905911

Locations in the U.S.

Conditions

• Allergy
• Anaphylaxis

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.