Home › Essential Tremor › NCT07911488

The Encora X1™ in a Real World Observational Study

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Age 18 years or older and able to comply with all study procedures
* A diagnosis of upper limb Essential Tremor (ET) as determined by clinical history
* A prescription for the Encora X1™
* Must have at least occasional access to a computer, tablet or smartphone, and be able to complete study questionnaires through the participant portal.
* Mentally competent to understand and able to perform written, informed consent (in English only) to participate in the study

Exclusion Criteria:

* Swollen, infected, inflamed areas, or skin eruptions, open wounds, or cancerous lesions of skin at stimulation site
* History of psoriasis, eczema or atopic dermatitis at the stimulation site
* History of peripheral neuropathy in the upper limbs, including carpal tunnel syndrome and diabetic neuropathy
* Pregnant women, or women who plan to become pregnant during their duration of the study
* Use of other External Upper Limb Tremor Stimulation Therapy during the course of the study
* Patient unable to communicate with sponsor/investigator and study staff
* Any other medical conditions or physical or mental impairments that in the sponsor/investigator's opinion would render the participant unsuitable as a candidate for the study.

About the study

This research is a post-market study designed to evaluate the long-term, real-world impact of the Encora X1™ on your daily life. The Encora X1™ is a FDA-cleared, wrist-worn, non-invasive neurostimulator device that delivers personalized mechanical stimulation to aid in the relief of hand tremors in adults with essential tremor. A non-invasive device is a device that stays outside of the body. It is not implanted and does not penetrate the skin. Neurostimulation means that the device uses targeted electrical or magnetic pulses to stimulate activity in the nervous system.

This study aims to understand how it improves your ability to perform daily activities and your overall satisfaction with the device over a 36-month period. Your feedback will help researchers understand how the device is used over a long period of time in a home environment and improve the delivery of care for individuals with Essential Tremor.

What is being tested

• Encora X1 (device)

Sponsor: Encora, Inc. · Participants: 1,000 · Started: Nov 1, 2026

Contact the study team

• Alexis Noyes · Phone: 413-529-6728

Official record on ClinicalTrials.gov — NCT07911488

Locations in the U.S.

Conditions

• Essential Tremor

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.