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Rehabilitation Program for People With Methamphetamine-Associated Cardiopulmonary Conditions
Feasibility of a Remote Collaborative Care-Facilitated Contingency Management-Exercise Rehabilitation Program for People With Methamphetamine-Associated Cardiopulmonary Conditions
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Active methamphetamine use determined by positive urine drug testing within the past 3 months and/or self-reported current use * Current diagnosis of chronic heart failure or pulmonary hypertension documented in the electronic health record * Possession of a smartphone * Able to participate in virtual exercise rehabilitation Exclusion Criteria: * Currently incarcerated * Unable to interact with smartphone app and/or virtual health coaching sessions in English * Unstable arrhythmia, defined as any known arrhythmia that is associated with hemodynamic effects like syncope, hypotension, or decompensated heart failure * Decompensated chronic heart failure or pulmonary hypertension * NYHA class IV symptoms * Myocardial infarction within the past 3 months, percutaneous coronary intervention within the past 2 weeks, coronary artery bypass graft within the past 3 months, or implantable cardiac defibrillator/cardiac resynchronization therapy/pacemaker implantation within the last 6 weeks * Unstable angina, uncontrolled hypertension, acute myocarditis/pericarditis, intracardiac thrombus * Severe symptomatic aortic stenosis
About the study
The purpose of this study is to evaluate the feasibility and preliminary effectiveness of increasing control over stimulant use and physical health through incentivized rehabilitation (INSPIRE). INSPIRE is a 12-week remotely-delivered collaborative care intervention for rural patients with Methamphetamine-Associated Heart Failure (Me-HF) or Methamphetamine-Associated Pulmonary Arterial Hypertension (Me-PAH) featuring smartphone-based contingency management incentivizing participation in remote synchronous rehabilitation.
What is being tested
- Increasing control over stimulant use and physical health through incentivized rehabilitation (behavioral)
- Usual Care (other)
Sponsor: Michael Incze · Participants: 45 · Started: Oct 13, 2026
Contact the study team
- Michael A Incze, MD · Phone: 801-581-2000
Official record on ClinicalTrials.gov — NCT07915882
Locations in the U.S.
| Utah | University of Utah Health, Salt Lake City |
Conditions
From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.