Home › Sexual Problems in Men › NCT07920900
PRP for Sexual Function
Vaginal Injection of Platelet Rich Plasma for Sexual Dysfunction: A Randomized Control Trial
Who can join
Ages 18 and older · Women
Full eligibility criteria
Inclusion Criteria: * Female, 18 years of age or older, presenting with sexual dysfunction * FSFI total score ≤ 26.5 * English speaking and literate Exclusion Criteria: * Unwilling or unable to provide informed consent * Pregnant or less than 12 weeks postpartum * Known history of bleeding disorder
About the study
This randomized, single-blinded, sham-controlled trial evaluates whether a single injection of autologous platelet-rich plasma (PRP) into the distal anterior vaginal wall improves sexual function in women with sexual dysfunction. Sixty participants with a Female Sexual Function Index (FSFI) total score of 26.5 or lower are randomized 1:1 to PRP injection or sterile saline injection. Sexual function, sexual distress, global impression of change, and urinary incontinence symptoms are assessed at baseline, 6 weeks, and 6 months after injection.
What is being tested
- Autologous Platelet-Rich Plasma (PRP) Injection (biological)
- Sterile saline injection (other)
Sponsor: Icahn School of Medicine at Mount Sinai · Participants: 60 · Started: Aug 27, 2026
Contact the study team
- Yara Sifri, MD · Phone: 978-273-1786
Official record on ClinicalTrials.gov — NCT07920900
Locations in the U.S.
| New York | The Mount Sinai Hospital, New York |
Conditions
From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.