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Glioma clinical trials in Ohio

18 studies for Glioma are looking for participants at sites in Ohio.

Cities in Ohio

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

  • Children's Hospital Medical Center of Akron, Akron
  • Cincinnati Children's Hospital Medical Center, Cincinnati
  • Rainbow Babies and Childrens Hospital, Cleveland
  • and 3 more
RecruitingPhase 1/2
12 Months – 21 Years · All sexes · Updated Oct 1, 2026 · NCT05099003

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

  • Cleveland Clinic Taussig Cancer Center, Cleveland
  • Ohio State University, Columbus
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07326566

ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

  • Cincinnati Children's Hospital, Cincinnati
  • Nationwide Children's Hospital, Columbus
RecruitingPhase 2
12 Months – 39 Years · All sexes · Updated Sep 21, 2026 · NCT06838676

Development of MRF for Characterization of Brain Tumors After Radiotherapy

  • University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center, Cleveland
  • Cleveland Clinic Taussig Cancer Center, Cleveland
RecruitingHealthy volunteers welcome
Ages 18 to 60 · All sexes · Updated Sep 15, 2026 · NCT06101069

Targeted Pediatric High-Grade Glioma Therapy

  • Cincinnati Children's Hospital Medical Center, Cincinnati
  • Nationwide Children's Hospital, Columbus
RecruitingObservational study
12 Months – 39 Years · All sexes · Updated Sep 8, 2026 · NCT05839379

Study of Olutasidenib and Temozolomide in HGG

  • Cincinnati Children's Hospital Medical Center, Cincinnati
  • Nationwide Children's Hospital, Columbus
RecruitingPhase 2
Ages 12 to 39 · All sexes · Updated Sep 1, 2026 · NCT06161974

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

  • Cleveland Clinic, Cleveland
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT05303519

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

  • Cincinnati Children's Hospital Medical Center, Cincinnati
  • Nationwide Children's Hospital, Columbus
RecruitingPhase 2
Ages 3 to 39 · All sexes · Updated Aug 24, 2026 · NCT05096481

Prospective Surgical Study on the Pattern of Electrical Activity in High Grade Glioma as a Predictor of Progression

  • Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center, Cleveland
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT05565118

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

  • Nationwide Children's Hospital, Colombus
  • The Ohio State University Comprehensive Cancer Center (OSUCCC) - The James Cancer Hospital and Solove Research Institute, Columbus
  • Taylor Cancer Research Center, Maumee
RecruitingPhase 2
Ages 8 and older · All sexes · Updated Jul 27, 2026 · NCT05503797

Alpha Radiation Emitters Device (DaRT) for the Treatment of Recurrent Glioblastoma

  • Ohio State University Medical Center, Columbus
Recruiting
Ages 18 to 85 · All sexes · Updated Jul 21, 2026 · NCT06910306

Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

  • Cincinnati Children's Hospital Medical Center, Cincinnati
  • Nationwide Children's Hospital, Columbus
RecruitingPhase 1/2
Ages 4 to 39 · All sexes · Updated Jul 20, 2026 · NCT05278208

Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

  • Cincinnati Children's Hospital Medical Center, Cincinnati
  • Nationwide Children's Hospital, Columbus
RecruitingEarly phase 1Healthy volunteers welcome
Ages 1 to 21 · All sexes · Updated Jun 29, 2026 · NCT06333899

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

  • Cincinnati Children's Hospital Medical Center, Cincinnati
  • Nationwide Children's Hospital, Columbus
RecruitingPhase 2
12 Months – 39 Years · All sexes · Updated May 29, 2026 · NCT05843253

Anti-GARP Chimeric Antigen Receptor T Cell Therapy for the Treatment of Recurrent Grade III or IV Gliomas

  • Ohio State University Comprehensive Cancer Center, Columbus
RecruitingPhase 1
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT06964737

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

  • Ohio State University Comprehensive Cancer Center, Columbus
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06810544

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

  • Cincinnati Children's Hospital Medical Center, Cincinnati
  • Nationwide Children's Hospital, Columbus
RecruitingEarly phase 1
Up to age 21 · All sexes · Updated Mar 18, 2026 · NCT04655404

Phase 1 Study of Locoregional Injections of Ex Vivo Expanded Natural Killer Cells

  • Nationwide Children's Hospital, Columbus
RecruitingPhase 1
12 Months – 39 Years · All sexes · Updated May 13, 2025 · NCT04254419

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.