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Liver Cancer (Hepatocellular Carcinoma) clinical trials in New York

33 studies for Liver Cancer (Hepatocellular Carcinoma) are looking for participants at sites in New York.

Cities in New York

A Study of ZW251 in Participants With Advanced Solid Tumors

  • Memorial Sloan Kettering Cancer Center, New York
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07164313

A Phase 1 Study of the Safety and Tolerability of CTX-10726

  • START New York, Lake Success
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07419841

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

  • Exelixis Clinical Site #60, New York
  • Exelixis Clinical Site #6, New York
  • Exelixis Clinical Site #76, Syracuse
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

Study of the Theranostic Pair RYZ811 (Diagnostic) and RYZ801 (Therapeutic) to Identify and Treat Subjects With GPC3+ (Glypican-3) Unresectable HCC

  • Research Facility, New York
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06726161

National Liver Cancer Screening Trial

  • The Feinstein Institutes, Northwell Health, Inc., Manhasset
RecruitingPhase 4
Ages 18 to 85 · All sexes · Updated Sep 25, 2026 · NCT06084234

Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations

  • Columbia University Irving Medical Center, New York
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06915753

A Phase 1/2 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors

  • Memorial Sloan Kettering Cancer Center Mskcc, New York
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT06427941

Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

  • NYU Langone Health, New York
  • Columbia University Irving Medical Center, New York
  • Memorial Sloan Kettering Cancer Center, New York
  • and 2 more
RecruitingObservational study
Ages 22 and older · All sexes · Updated Sep 11, 2026 · NCT06486454

GPC3-Targeted T-Cell Therapy (ECT204) in Adults With Advanced HCC

  • Montefiore Einstein Comprehensive Cancer Center, The Bronx
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT04864054

Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma

  • Research Site, New York
  • Research Site, New York
  • Research Site, New York
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06921785

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

  • New York Cancer & Blood Specialists, New York
  • University of Rochester - Wilmot Cancer Institute, Rochester
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT06582017

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York
RecruitingPhase 1/2
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

FOG-001 in Locally Advanced or Metastatic Solid Tumors

  • Memorial Sloan Kettering Cancer Center, New York
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial

  • Northwell Health/Center for Advanced Medicine, Lake Success
  • Mount Sinai Hospital, New York
  • Montefiore Medical Center-Einstein Campus, The Bronx
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07166406

A Study of MGC026 in Participants With Advanced Solid Tumors

  • START-New York Long Island, Lake Success
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT06242470

HepQuant: Study to Assess the Role of Blood-based Biomarkers and Quantitative MR Imaging for Patients Receiving Radiation Therapy for Liver Cancer

  • Montefiore Medical Center, The Bronx
Recruiting
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT06899152

A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)

  • NYU Langone Health, New York
  • Icahn School of Medicine At Mount Sinai Prime, New York
  • Clinical Research Alliance, Inc, Westbury
  • and 1 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06330064

Atezolizumab in Combination With a Multi-Kinase Inhibitor for the Treatment of Unresectable, Locally Advanced, or Metastatic Liver Cancer

  • Roswell Park Cancer Institute, Buffalo
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT05168163

Atezolizumab and Bevacizumab in Combination With Y^90 Radioembolization in HCC for Liver Transplant

  • Icahn School of Medicine at Mount Sinai, New York
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Jul 28, 2026 · NCT07059494

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

  • Columbia University Irving Medical Center, New York
  • Memorial Sloan Kettering Cancer Center, New York
RecruitingPhase 2
Ages 8 and older · All sexes · Updated Jul 27, 2026 · NCT05503797

A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma

  • Clinical Trial Site, New York
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 17, 2026 · NCT06600321

Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

  • VA NY Harbor Healthcare System, New York, NY, New York
  • James J. Peters VA Medical Center, Bronx, NY, The Bronx
Recruiting
Ages 18 to 75 · All sexes · Updated Jun 17, 2026 · NCT05486572

A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies

  • Memorial Sloan Kettering Cancer Center, New York
RecruitingPhase 1
Ages 16 and older · All sexes · Updated Jun 2, 2026 · NCT07197554

DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

  • USA04-0, New York
RecruitingPhase 2
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06953089

A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma

  • Memorial Sloan Kettering Cancer Center - New York, New York
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Apr 27, 2026 · NCT05440708

Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC

  • Roswell Park Comprehensive Cancer Center, Buffalo
  • Montefiore Medical CenterMontefiore Medical Park, The Bronx
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Apr 2, 2026 · NCT05733598

Tislelizumab Consolidation After Liver-Directed Therapy for Hepatocellular Carcinoma

  • Montefiore Medical Center, The Bronx
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jan 20, 2026 · NCT05366829

HOPE Against Cancer Recurrence in HCC

  • Rutgers New Jersey Medical School (New York), New York
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Dec 16, 2025 · NCT06717919

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

  • Research Site 107, New York
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

  • Massive Bio SYNERGY-AI site, Buffalo
  • Massive Bio SYNERGY-AI site, Hempstead
  • Massive Bio SYNERGY-AI site, Manhasset
  • and 2 more
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

The Dragon PLC Trial (DRAGON-PLC)

  • Memorial Sloan Kettering Cancer Center, New York
Recruiting
Ages 18 and older · All sexes · Updated May 15, 2025 · NCT06914648

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.