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Post-Lyme Disease Syndrome clinical trials recruiting in the U.S.
8 studies for Post-Lyme Disease Syndrome are recruiting participants at sites across the United States.
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Recently updated studies
Navigating Pregnancy and Parenthood With Lyme Disease
RecruitingObservational study
Ages 18 and older · Women · Updated Jun 17, 2026 · NCT06397794Pregnancy and Early Neurodevelopmental Outcomes Following In Utero Lyme Disease Exposure
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 16, 2026 · NCT06026969Sana Device for Post-Treatment Lyme Disease Syndrome Chronic Pain
Recruiting
Ages 18 and older · All sexes · Updated May 18, 2026 · NCT06655844taVNS for Persistent Symptoms From Lyme Disease
Recruiting
Ages 18 to 65 · All sexes · Updated May 6, 2026 · NCT05776251Transcranial Direct Current Stimulation for Post Treatment Lyme Disease
Recruiting
Ages 18 to 70 · All sexes · Updated May 6, 2026 · NCT06915324Ceftriaxone Pulse Dose for Post-Treatment Lyme Disease
RecruitingEarly phase 1
Ages 18 to 75 · All sexes · Updated Mar 19, 2026 · NCT06611111Lumbrokinase for Adults With Long Covid, Post-treatment Lyme Disease Syndrome, and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Mar 13, 2026 · NCT06511050Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
RecruitingObservational studyHealthy volunteers welcome
Ages 2 and older · All sexes · Updated Jan 22, 2026 · NCT04806620From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.