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Preterm Premature Rupture of the Membranes clinical trials recruiting in the U.S.
6 studies for Preterm Premature Rupture of the Membranes are recruiting participants at sites across the United States.
Recently updated studies
Extended Azithromycin Treatment in Prelabor Rupture of Membranes
RecruitingPhase 4
All ages · Women · Updated Sep 4, 2026 · NCT07669207PPROM Registry (Preterm Premature Rupture of Membranes)
RecruitingObservational studyHealthy volunteers welcome
Ages 14 to 55 · Women · Updated Mar 16, 2026 · NCT02997345Improvement of PPROM Management With Prophylactic Antimicrobial Therapy (iPROMPT)
RecruitingPhase 4
Ages 18 and older · Women · Updated Jan 27, 2026 · NCT06396078Digital vs. Speculum Exams for PPROM
RecruitingHealthy volunteers welcome
All ages · Women · Updated Jan 5, 2026 · NCT05773014Oxytocin/Foley vs. Oxytocin for Induction in Patients With PPROM
RecruitingPhase 4
Ages 18 to 50 · Women · Updated Aug 13, 2025 · NCT07119398Latency Antibiotics in Previable PPROM, 18 0/7- 22 6/7 WGA
RecruitingPhase 4Healthy volunteers welcome
Ages 18 and older · Women · Updated Jan 11, 2021 · NCT04047849From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.