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Healthy volunteer studies in Greenville, SC

16 studies at sites in and around Greenville accept healthy volunteers — people without the condition being studied. Many studies pay participants for their time and travel; the amount is set by each study, so ask the study team.

Education & Mentorship of Advanced Practice Providers to Increase Community-based Research Within the NCORP Network, COACH-APP Trial

RecruitingHealthy volunteers welcome
  • Prisma Health Cancer Institute - Faris, Greenville
  • Prisma Health Cancer Institute - Eastside, Greenville
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06904391

A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)

RecruitingPhase 1Healthy volunteers welcome
  • Tribe Clinical Research, LLC-Pediatrics ( Site 1008), Greenville
2 Months – 15 Months · All sexes · Updated Oct 2, 2026 · NCT07300267

Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study

RecruitingObservational studyHealthy volunteers welcome
  • Prisma Health Greenville Memorial Hospital, Greenville
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07215624

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

RecruitingHealthy volunteers welcome
  • Prisma Health Cancer Institute - Butternut, Greenville
  • Prisma Health Cancer Institute - Faris, Greenville
  • Prisma Health Cancer Institute - Eastside, Greenville
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07283939

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Prisma Health Cancer Institute - Faris, Greenville
  • Prisma Health Greenville Memorial Hospital, Greenville
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Buprenorphine Implementation at Syringe Service Programs to Reduce Overdoses

RecruitingHealthy volunteers welcome
  • Challenges, Inc/Prisma Health, Greenville
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07631598

Comparison of Two Different Sperm Processing Methods and Their Effects on Sperm DNA Fragmentation and Embryo Development

RecruitingHealthy volunteers welcome
  • Prisma Health-Upstate Fertility Center of the Caroliinas, Greenville
Ages 18 to 34 · All sexes · Updated Sep 24, 2026 · NCT06990841

A Phase 3 Study of Revaccination in Subsequent Pregnancies With Bivalent RSV Vaccine and Duration of Protection of a Single Dose

RecruitingPhase 3Healthy volunteers welcome
  • Prisma Health Maternal Fetal Medicine, Greenville
  • Prisma Health OBGYN Center, Greenville
Ages 0 and older · All sexes · Updated Sep 24, 2026 · NCT06866405

A Study of BLB-201 RSV Vaccine in Infants and Children

RecruitingPhase 1/2Healthy volunteers welcome
  • Tribe Clinical Research, LLC Parkside Pediatrics Verdae, Greenville
  • Tribe Clinical Research, LLC Parkside Pediatrics, Greenville
6 Months – 5 Years · All sexes · Updated Sep 23, 2026 · NCT05655182

Comparing Telephone Symptom Monitoring Interventions for Managing Symptoms and Psychological Distress During Oral Anti-Cancer Treatment

RecruitingHealthy volunteers welcome
  • Prisma Health Cancer Institute - Butternut, Greenville
  • Prisma Health Cancer Institute - Faris, Greenville
  • Prisma Health Greenville Memorial Hospital, Greenville
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06279013

STEPS: Substance Use Trial of E-cigarettes or Pharmacotherapy for Smoking

RecruitingHealthy volunteers welcome
  • Phoenix Center, Greenville
Ages 21 and older · All sexes · Updated Sep 3, 2026 · NCT06922617

A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease

RecruitingPhase 1/2Healthy volunteers welcome
  • Local Institution - 0027, Greenville
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT06481306

Robotic Versus Open Ventral Hernia Repair

RecruitingHealthy volunteers welcome
  • Prisma Health Greenville Memorial Hospital, Greenville
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT05472987

A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age

RecruitingPhase 3Healthy volunteers welcome
  • GSK Investigational Site, Greenville
12 Months – 15 Months · All sexes · Updated May 29, 2026 · NCT06740630

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

RecruitingPhase 3Healthy volunteers welcome
  • Saint Francis Hospital, Greenville
  • Prisma Health Cancer Institute - Butternut, Greenville
  • Prisma Health Cancer Institute - Faris, Greenville
  • and 2 more
Ages 18 and older · All sexes · Updated Mar 31, 2026 · NCT07018869

Prevent Cancer- Greenville

RecruitingObservational studyHealthy volunteers welcome
  • Prisma Health-Upstate, Greenville
Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT04947098

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.