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Non-Small Cell Lung Cancer clinical trials in Arizona

66 studies for Non-Small Cell Lung Cancer are looking for participants at sites in Arizona.

Cities in Arizona

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

  • Banner Boswell Medical Center, Sun City
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT04267848

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

  • Banner MD Anderson Cancer Center ( Site 0181), Gilbert
  • The University of Arizona Cancer Center - North Campus ( Site 0163), Tucson
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06623422

Phase 1/2 Study of Intravenous Injection of STX-003 in Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab

  • HonorHealth Research Institute, Scottsdale
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07751042

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

  • Exelixis Clinical Site #67, Phoenix
  • Exelixis Clinical Site #1, Tucson
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

A Platform Study in Non-Small Cell Lung Cancer (NSCLC)

  • Research Site, Phoenix
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06996782

A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

  • Mohtaseb Cancer Center & Blood Disorders, Bullhead City
  • Palo Verde Hematology Oncology, Glendale
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07361510

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

  • Palo Verde Hematology Oncology, Glendale
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06765109

A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

  • Research Site, Gilbert
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05877599

Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

  • Pioneer Research Center, Bullhead City
  • Ironwood Cancer & Research Centers, Chandler
  • Ironwood Cancer & Research Centers, Gilbert
  • and 6 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07222566

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

  • Banner Health, Gilbert
  • Mayo Clinic Hospital, Phoenix
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT04981119

A Study to Investigate Ubamatamab With and Without Marlotamig (REGN7075) in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

  • Cancer Treatment Centers of America, Phoenix, Goodyear
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07154290

Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

  • City of Hope, Phoenix, Phoenix
  • The University of Arizona Cancer Center - North Campus, Tucson
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06890598

Pan-tumor MRD Study

  • Mohtaseb Cancer Center and Blood Disorders, Bullhead City
  • Cancer & Blood Specialists of Arizona, Casa Grande
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06605404

Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors

  • Banner MD Anderson Cancer Center, Gilbert
  • Arizona Cancer Center at UMC North/University Medical Center, Tucson
RecruitingPhase 1/2
Ages 18 to 99 · All sexes · Updated Sep 22, 2026 · NCT06814496

A Study of SHY-ONC6, a Novel Proteasome Inhibitor, in Adults With Advanced or Metastatic Solid Tumors

  • HonorHealth Research Institute, Scottsdale
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07705334

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

  • Clinical Study Site, Chandler
  • Clinical Study Site, Phoenix
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT06767514

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

  • Banner Health- MD Anderson Cancer Center, Gilbert
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05786924

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

  • Local Institution - 007-556-A, Goodyear
  • USOR - Arizona Oncology - Prescott Valley, Prescott Valley
  • Local Institution - 007-568-A, Safford
  • and 5 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT04613596

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

  • Ironwood Cancer & Research Centers, Chandler
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

A Study of KK2269 in Adult Participants With Solid Tumors

  • Mayo Clinic Arizona, Scottsdale
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06266299

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

  • Banner MD Anderson Cancer Center, Gilbert
  • Banner University Medical Center Phoenix, Phoenix
  • The University of Arizona Cancer Center - North Campus, Tucson
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

A Study of a Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors

  • HonorHealth Research Institute, Scottsdale
  • Mayo Scottsdale, Scottsdale
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07361562

A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

  • HonorHealth, Scottsdale
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06400472

Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

  • Research Site, Chandler
  • Research Site, Gilbert
  • Research Site, Goodyear
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07291037

Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

  • Mayo Clinic, Phoenix
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT05245500

A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer

  • Mayo Clinic Arizona, Phoenix
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT06892548

A Phase 1 and 2 Study of VMD-102 in Hepatocellular Carcinoma and Other Solid Tumors

  • HonorHealth Research Institute, Scottsdale
RecruitingPhase 1/2
Ages 18 to 75 · All sexes · Updated Aug 19, 2026 · NCT07636785

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

  • Mayo Clinic Hospital in Arizona, Phoenix
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06500481

A Study of BH-30643 in Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations

  • Mayo Clinic Hospital - Arizona, Phoenix
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06706076

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

  • USOR HonorHealth, Phoenix
  • USOR Arizona Oncology Associates, Tucson
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT05579366

AOH1996 for the Treatment of Refractory Solid Tumors

  • Honor Health Research and Innovation Institute, Scottsdale
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 28, 2026 · NCT05227326

A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

  • Mayo Clinic Hospital, Phoenix
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT06179160

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.