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Клинични проучвания за Остра миелоидна левкемия в Северна Каролина

43 проучвания за Остра миелоидна левкемия търсят участници в обекти в Северна Каролина.

Градове в Северна Каролина

Официален текст на проучването (английски)

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

  • AdventHealth Infusion Center Asheville, Asheville
  • Southeastern Medical Oncology Center-Clinton, Clinton
  • AdventHealth Infusion Center Haywood, Clyde
  • и още 6
Набиране на участнициНаблюдателно проучванеЗдравите доброволци са добре дошли
Възраст от 40 до 75 · Всички полове · Обновено на 2.10.2026 г. · NCT05334069

Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes

  • Wake Forest University Health Sciences, Winston-Salem
Набиране на участнициФаза 1
Възраст 18 и повече · Всички полове · Обновено на 1.10.2026 г. · NCT06484062

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • Novant Health Presbyterian Medical Center, Charlotte
  • Duke University Medical Center, Durham
  • и още 3
Набиране на участнициФаза 2
Възраст от 18 до 59 · Всички полове · Обновено на 28.09.2026 г. · NCT05554393

A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

  • Atrium Health, Charlotte
  • Novant Health Charlotte, Charlotte
  • Carolina Oncology Specialists, Charlotte
  • и още 2
Набиране на участнициФаза 3
Възраст 18 и повече · Всички полове · Обновено на 25.09.2026 г. · NCT06852222

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill
  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • Novant Health Presbyterian Medical Center, Charlotte
  • и още 5
Набиране на участнициФаза 2
Възраст 18 и повече · Всички полове · Обновено на 25.09.2026 г. · NCT05564390

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • Duke University Medical Center, Durham
  • East Carolina University, Greenville
  • и още 1
Набиране на участнициФаза 2
Възраст 18 и повече · Всички полове · Обновено на 22.09.2026 г. · NCT06317649

Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)

  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • Duke University Medical Center, Durham
  • East Carolina University, Greenville
  • и още 1
Набиране на участнициФаза 2
Възраст 18 и повече · Всички полове · Обновено на 22.09.2026 г. · NCT06672146

Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)

  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • Duke University Medical Center, Durham
  • East Carolina University, Greenville
  • и още 1
Набиране на участнициФаза 2
Възраст от 18 до 59 · Всички полове · Обновено на 22.09.2026 г. · NCT05554406

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

  • Mission Hospital, Asheville
  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill
  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • и още 4
Набиране на участнициФаза 3
6 Months – 21 Years · Всички полове · Обновено на 17.09.2026 г. · NCT04293562

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

  • Duke University Medical Center, Durham
Набиране на участнициФаза 1/2
30 Days · Всички полове · Обновено на 16.09.2026 г. · NCT04065399

Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Complete Remission

  • Novant Health Clinical Research, Charlotte
  • East Carolina University, Greenville
Набиране на участнициФаза 2
Възраст 18 и повече · Всички полове · Обновено на 16.09.2026 г. · NCT06824168

Phase 1 Study of AUTX-703 in Relapsed/Refractory AML and MDS

  • University of North Carolina at Chapel Hill, Chapel Hill
Набиране на участнициФаза 1
Възраст 18 и повече · Всички полове · Обновено на 14.09.2026 г. · NCT06846606

Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML

  • UNC School of Medicine, Division of Hematology, Chapel Hill
Набиране на участнициФаза 1/2
Възраст 12 и повече · Всички полове · Обновено на 3.09.2026 г. · NCT04588922

A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies

  • Novant Health Weisiger Cancer Institute, Charlotte
Набиране на участнициНаблюдателно проучване
Възраст 0 и повече · Всички полове · Обновено на 2.09.2026 г. · NCT07154823

Olutasidenib in Relapsed IDH1 Mutated AML Patients Who Have Previously Received Venetoclax

  • Atrium Health Wake Forest Baptist Medical Center, Winston-Salem
Набиране на участнициФаза 2
Възраст 18 и повече · Всички полове · Обновено на 2.09.2026 г. · NCT07471841

Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML

  • US-Chapel Hill-UNCNORTHCAROLINA, Chapel Hill
Набиране на участнициФаза 3
Възраст 18 и повече · Всички полове · Обновено на 2.09.2026 г. · NCT06652438

A Phase 1b Study of Menin Inhibitor SNDX- 5613 in Combination With Daunorubicin and Cytarabine in Newly Diagnosed Patients With Acute Myeloid Leukemia and NPM1 Mutated/FLT3 Wildtype or MLL/KMT2A Rearranged or NUP98 Alterations Disease

  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill
  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • Wake Forest University Health Sciences, Winston-Salem
Набиране на участнициФаза 1
Възраст от 18 до 75 · Всички полове · Обновено на 25.08.2026 г. · NCT05886049

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

  • Mission Hospital, Asheville
  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill
  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • и още 4
Набиране на участнициФаза 1/2
До 22 години · Всички полове · Обновено на 25.08.2026 г. · NCT04726241

Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML

  • University of North Carolina, Chapel Hill, Chapel Hill
  • Duke University Medical Center, Durham
Набиране на участнициФаза 3
Възраст 18 и повече · Всички полове · Обновено на 20.08.2026 г. · NCT07007312

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

  • Atrium Health Levine Cancer Center, Charlotte
Набиране на участнициФаза 1
Възраст 18 и повече · Всички полове · Обновено на 20.08.2026 г. · NCT06001788

ICP-248 in Combination With Azacitidine for the Treatment in Patients With Myeloid Malignancies

  • University of North Carolina at Chapel Hill, Chapel Hill
Набиране на участнициФаза 1
Възраст 18 и повече · Всички полове · Обновено на 18.08.2026 г. · NCT06656494

Toxicity Genetic Determinants and Response to Azacitidine and Venetoclax in AML

  • Levine Cancer Institute, Charlotte
  • Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem
Набиране на участнициНаблюдателно проучване
Възраст 18 и повече · Всички полове · Обновено на 24.07.2026 г. · NCT06580106

ONC-LEUK-2406: The Impact of Systematic Financial Navigation in Acute Myeloid Leukemia

  • Levine Cancer Insitute, Charlotte
  • Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem
Набиране на участници
Възраст от 18 до 64 · Всички полове · Обновено на 23.07.2026 г. · NCT06945042

Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression

  • Research Site, Chapel Hill
  • Research Site, Durham
Набиране на участнициФаза 1/2
Възраст 16 и повече · Всички полове · Обновено на 20.07.2026 г. · NCT07155226

Tagraxofusp and Azacitidine With Venetoclax in Newly Diagnosed Secondary AML After Hypomethylating Agents

  • University of North Carolina at Chapel Hill, Chapel Hill
  • Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem
Набиране на участнициФаза 2
Възраст 18 и повече · Всички полове · Обновено на 10.07.2026 г. · NCT05442216

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

  • University of North Carolina at Chapel Hill, Chapel Hill
  • Levine Children's Hospital, Charlotte
  • Duke University Medical Center, Durham
Набиране на участнициНаблюдателно проучване
Всички възрасти · Всички полове · Обновено на 6.07.2026 г. · NCT01351545

A Decisional Intervention for Older Adults With Acute Myeloid Leukemia and Their Caregivers

  • University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill
  • Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Section of Hematology/Oncology, Winston-Salem
Набиране на участници
Възраст 60 и повече · Всички полове · Обновено на 6.07.2026 г. · NCT06697600

Registry of Older Patients With Cancer

  • Seby B. Jones Cancer Center, Boone
  • Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill
  • East Carolina University, Greenville
  • и още 4
Набиране на участнициНаблюдателно проучване
Възраст 65 и повече · Всички полове · Обновено на 29.06.2026 г. · NCT01137825

IDH Targeted/Non- Targeted vs Non-targeted/IDH-targeted Approaches in the Treatment of Newly Diagnosed IDH Mutated AML Patients Not Candidates for Intensive Induction Therapy (I- DATA Study)

  • UNC Hospitals, University of North Carolina at Chapel Hill, Chapel Hill
Набиране на участнициФаза 2
Възраст 18 и повече · Всички полове · Обновено на 23.06.2026 г. · NCT05401097

A Study of Revumenib and Mezigdomide in People With Leukemia

  • University of North Carolina (Data Collection Only), Chapel Hill
Набиране на участнициФаза 1/2
Възраст 12 и повече · Всички полове · Обновено на 22.06.2026 г. · NCT07356154

SNDX-5613 and Gilteritinib for the Treatment of Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia and Concurrent MLL-Rearrangement or NPM1 Mutation

  • UNC Hospitals, University of North Carolina at Chapel Hill, Chapel Hill
Набиране на участнициФаза 1
Възраст 18 и повече · Всички полове · Обновено на 14.05.2026 г. · NCT06222580

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

  • University of North Carolina, Chapel Hill
Набиране на участнициФаза 1
Възраст 13 и повече · Всички полове · Обновено на 5.05.2026 г. · NCT04771572

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

  • Duke University, Durham
Набиране на участнициФаза 2/3
Възраст 18 и повече · Всички полове · Обновено на 30.04.2026 г. · NCT04256317

The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen

  • Wake Forest Baptist Health, Winston-Salem
Набиране на участнициНаблюдателно проучване
Възраст от 18 до 120 · Всички полове · Обновено на 13.04.2026 г. · NCT01890486

A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

  • UNC Hospital, Chapel Hill
  • Duke University, Durham
  • Atrium Wake Forest Baptist Medical Center, Winston-Salem
Набиране на участнициФаза 1/2
Възраст 12 и повече · Всички полове · Обновено на 24.03.2026 г. · NCT04988555

A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation

  • University of North Carolina, Chapel Hill
Набиране на участнициФаза 2
Възраст от 18 до 66 · Всички полове · Обновено на 17.03.2026 г. · NCT06859424

A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

  • Duke Blood Cancer Center, Durham
Набиране на участнициФаза 1
Възраст 18 и повече · Всички полове · Обновено на 13.03.2026 г. · NCT05735184

CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

  • Duke Cancer Center, Durham
Набиране на участнициФаза 1
Възраст 18 и повече · Всички полове · Обновено на 16.01.2026 г. · NCT05143996

Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS

  • Novant Health Cancer Institute, Charlotte
  • Novant Health Cancer Institute, Winston-Salem
Набиране на участнициФаза 1/2
Възраст 18 и повече · Всички полове · Обновено на 10.12.2025 г. · NCT06680752

Novel Digital Application for Patients With Acute Leukemia

  • Duke University, Durham
Набиране на участници
Възраст от 18 до 120 · Всички полове · Обновено на 10.11.2025 г. · NCT06472128

От ClinicalTrials.gov, данни към 5.10.2026 г.. Всяко проучване има свои критерии за участие; екипът на проучването определя кой може да се включи.