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Brain Tumors clinical trials in North Carolina
20 studies for Brain Tumors are looking for participants at sites in North Carolina.
Cities in North Carolina
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
- Duke University School of Medicine, Durham
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05786924A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)
- Local Institution - 0100, Durham
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07492680A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases
- Wake Forest University at Clemmons, Clemmons
- Southeastern Medical Oncology Center-Clinton, Clinton
- Southeastern Medical Oncology Center-Goldsboro, Goldsboro
- and 4 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04511013A Phase 1/1b Study of IAM1363 in HER2 Cancers
- Duke Cancer Institute, Durham
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06253871Targeted Pediatric High-Grade Glioma Therapy
- Duke University Health System, Durham
RecruitingObservational study
12 Months – 39 Years · All sexes · Updated Sep 8, 2026 · NCT05839379A Study of Zanzalintinib in Participants With Recurrent or Progressive Meningioma
- Duke University, Durham
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07428616Study of Olutasidenib and Temozolomide in HGG
- Duke University Health System, Durham
RecruitingPhase 2
Ages 12 to 39 · All sexes · Updated Sep 1, 2026 · NCT06161974ViCToRy: Vorasidenib in Combination With Tumor Specific Peptide Vaccine for Recurrent IDH1 Mutant Lower Grade Gliomas
- Duke University Medical Center, Durham
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT05609994Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets
- Atrium Health Wake Forest Baptist, Winston-Salem
RecruitingPhase 3
Ages 18 to 100 · All sexes · Updated Aug 19, 2026 · NCT05317858MRI Biomarkers for Radiation-Induced Neurocognitive Decline Following SRS of Newly Diagnosed Brain Mets
- University of North Carolina at Chapel Hill, Department of Radiation Oncology, Chapel Hill
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT04073966B6 Administration for Levetiracetam-Associated Neurobehavioral Changes and Epilepsy
- Duke University Medical Center, Durham
Recruiting
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT07271966Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)
- Vidant Heath - ECU Medical Center, Greenville
- Atlantic Brain & Spine, Wilmington
RecruitingObservational study
All ages · All sexes · Updated Jul 22, 2026 · NCT04427384Reducing the Incidence of Symptomatic Brain Metastases With MRI Surveillance
- Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 17, 2026 · NCT05692635REMASTer: REcurrent Brain Metastases After SRS Trial
- Wake Forest Baptist Medical Center, Winston-Salem
Recruiting
Ages 18 and older · All sexes · Updated Jun 18, 2026 · NCT05124912Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases
- Cone Health Cancer Center, Greensboro
- Wake Forest University Health Sciences, Winston-Salem
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jun 9, 2026 · NCT03550391Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant
- Duke University Health System, Durham
RecruitingPhase 2
12 Months – 39 Years · All sexes · Updated May 29, 2026 · NCT05843253Autologous CAR-T Cells Targeting B7-H3 in Recurrent or Refractory GBM CAR.B7-H3Tc
- Lineberger Comprehensive Cancer Center, Chapel Hill
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT05366179Key Longitudinal Associations With Risk and Glioblastoma Outcomes
- Duke University, Durham
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jan 20, 2026 · NCT06625684Circulating Biomarkers Repository in Adults Diagnosed With Primary and Metastatic Brain Tumors
- Duke Cancer Center, Durham
RecruitingObservational study
Ages 18 and older · All sexes · Updated Nov 19, 2025 · NCT05480644APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
- University of North Carolina, Chapel Hill
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 27, 2025 · NCT03175224From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.