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Brain Tumors clinical trials recruiting in the U.S.
200 studies for Brain Tumors are recruiting participants at sites across the United States.
A brain tumor is a growth of abnormal cells in the brain tissue. Learn the types of tumors, symptoms, how they are diagnosed and treatment options.
Cities with the most studies
- Houston, TX37 studies
- Boston, MA29 studies
- New York City, NY25 studies
- Washington, DC21 studies
- Los Angeles, CA17 studies
- Durham, NC15 studies
- Miami, FL14 studies
- Chicago, IL12 studies
- Rochester, MN12 studies
- St. Louis, MO12 studies
- Cleveland, OH11 studies
- Columbus, OH11 studies
- Seattle, WA11 studies
- Ann Arbor, MI11 studies
- Baltimore, MD11 studies
- San Francisco, CA10 studies
- Aurora, CO10 studies
- Atlanta, GA9 studies
- Detroit, MI8 studies
- Portland, OR8 studies
- Jacksonville, FL8 studies
- Arlington, VA8 studies
- Minneapolis, MN8 studies
- Cincinnati, OH7 studies
- Philadelphia, PA7 studies
- Baldwin Park, CA7 studies
- Mountain View, CA7 studies
- Dallas, TX7 studies
- San Diego, CA7 studies
- Tampa, FL7 studies
- Salt Lake City, UT7 studies
- Madison, WI6 studies
- Nashville, TN6 studies
- San Antonio, TX6 studies
- Winston-Salem, NC6 studies
- Scottsdale, AZ5 studies
- Milwaukee, WI5 studies
- Pittsburgh, PA5 studies
- Birmingham, AL5 studies
- Dayton, OH4 studies
By state
- Alabama5 studies
- Arizona11 studies
- Arkansas3 studies
- California40 studies
- Colorado12 studies
- District of Columbia14 studies
- Florida28 studies
- Georgia11 studies
- Idaho3 studies
- Illinois15 studies
- Indiana3 studies
- Iowa4 studies
- Kansas3 studies
- Kentucky4 studies
- Maryland18 studies
- Massachusetts30 studies
- Michigan18 studies
- Minnesota20 studies
- Missouri13 studies
- Montana3 studies
- Nebraska5 studies
- New Hampshire4 studies
- New Jersey9 studies
- New York34 studies
- North Carolina21 studies
- Ohio23 studies
- Oklahoma3 studies
- Oregon8 studies
- Pennsylvania14 studies
- Rhode Island3 studies
- South Carolina5 studies
- Tennessee10 studies
- Texas42 studies
- Utah8 studies
- Virginia15 studies
- Washington12 studies
- Wisconsin12 studies
Recently updated studies
000860: A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations
RecruitingPhase 1/2
Ages 15 to 99 ยท All sexes ยท Updated Nov 12, 2026 ยท NCT05588141Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Nov 12, 2026 ยท NCT07326566S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 12, 2026 ยท NCT03418961Tumor Related Epilepsy
RecruitingObservational study
Ages 8 to 99 ยท All sexes ยท Updated Nov 12, 2026 ยท NCT02639325Evaluation and Treatment of Neurosurgical Disorders
RecruitingObservational study
Ages 4 to 99 ยท All sexes ยท Updated Nov 10, 2026 ยท NCT00060541A Phase I Clinical Study of YN003 in the Treatment of Glioma
RecruitingPhase 1
Ages 18 to 70 ยท All sexes ยท Updated Nov 10, 2026 ยท NCT07929909Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors
Recruiting
Ages 18 and older ยท All sexes ยท Updated Nov 10, 2026 ยท NCT02754544A Comprehensive Clinical fMRI Software Solution to Enable Mapping of Critical Functional Networks and Cerebrovascular Reactivity in the Brain
RecruitingObservational study
Ages 18 and older ยท All sexes ยท Updated Nov 10, 2026 ยท NCT05342454Virtual Home-based Exercise Intervention (RISE) to Improve Cancer-Related Cognitive Impairment and Gut Microbiome in Adolescent and Young Adult Brain Tumor Survivors
Recruiting
Ages 15 to 39 ยท All sexes ยท Updated Nov 6, 2026 ยท NCT06799481PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications
RecruitingPhase 1/2
Ages 18 to 120 ยท All sexes ยท Updated Nov 6, 2026 ยท NCT06161519cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
RecruitingObservational studyHealthy volunteers welcome
Ages 40 and older ยท All sexes ยท Updated Nov 4, 2026 ยท NCT05366881A Study of Navlimetostat (BMS-986504) Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Nov 4, 2026 ยท NCT07492680Living Well With Brain Cancer: A Group-Based Intervention to Promote Whole-Person Well-Being
Recruiting
Ages 18 and older ยท All sexes ยท Updated Nov 3, 2026 ยท NCT07628647Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer
RecruitingPhase 1
Ages 3 to 25 ยท All sexes ยท Updated Nov 2, 2026 ยท NCT05106296Mapping of Human Cognition
Recruiting
Ages 18 to 75 ยท All sexes ยท Updated Nov 2, 2026 ยท NCT05989893A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)
RecruitingPhase 1
Ages 4 and older ยท All sexes ยท Updated Oct 30, 2026 ยท NCT04573140rTMS for Postoperative Brain Tumor Patients
Recruiting
Ages 22 to 65 ยท All sexes ยท Updated Oct 29, 2026 ยท NCT07530536Brain [18F]-FES PET/CT in Patients With Estrogen-Receptor Positive Breast Cancer
RecruitingPhase 4
Ages 18 and older ยท Women ยท Updated Oct 29, 2026 ยท NCT06072807An Exercise Intervention for Improving Mental and Physical Health in Patients With Primary Brain Tumors and Their Caregivers, ET-NEURO Trial
RecruitingHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Oct 28, 2026 ยท NCT07278440Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).
RecruitingPhase 2
Ages 1 to 26 ยท All sexes ยท Updated Oct 28, 2026 ยท NCT07680439A Study of Zanzalintinib in Participants With Recurrent or Progressive Meningioma
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Oct 28, 2026 ยท NCT07428616Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss
RecruitingPhase 1/2
Ages 18 and older ยท All sexes ยท Updated Oct 21, 2026 ยท NCT06810544Safety & Efficacy/Tolerability of Rhenium-186 NanoLiposomes (186RNL) for Patients Who Received a Prior 186RNL Treatment
RecruitingPhase 1
Ages 18 and older ยท All sexes ยท Updated Oct 21, 2026 ยท NCT05460507EXercise-induced PhysioLogical Adaptations In Neurological Disorders
RecruitingHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Oct 20, 2026 ยท NCT07883720Development of MRF for Characterization of Brain Tumors After Radiotherapy
RecruitingHealthy volunteers welcome
Ages 18 to 60 ยท All sexes ยท Updated Oct 20, 2026 ยท NCT06101069From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.