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Lung Cancer clinical trials in Milwaukee, WI

21 studies for Lung Cancer are looking for participants at sites in and around Milwaukee (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Zablocki Veterans Administration Medical Center, Milwaukee
Ages 45 to 75 · All sexes · Updated Oct 5, 2026 · NCT06995898

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

RecruitingPhase 3
  • Aurora Cancer Care-Milwaukee, Milwaukee
  • Aurora Saint Luke's Medical Center, Milwaukee
  • Aurora Sinai Medical Center, Milwaukee
  • and 8 more
Ages 70 and older · All sexes · Updated Oct 5, 2026 · NCT06096844

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

RecruitingPhase 3
  • Aurora Cancer Care-Milwaukee, Milwaukee
  • Ascension Columbia Saint Mary's Hospital-Milwaukee Campus, Milwaukee
  • Aurora Saint Luke's Medical Center, Milwaukee
  • and 13 more
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT04267848

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

RecruitingPhase 3
  • Medical College of Wisconsin, Milwaukee
  • ProHealth Waukesha Memorial Hospital, Waukesha · 17 mi away
  • UW Cancer Center at ProHealth Care, Waukesha · 17 mi away
  • and 1 more
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT04181060

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Aurora Cancer Care-Milwaukee, Milwaukee
  • Aurora Saint Luke's Medical Center, Milwaukee
  • Aurora Sinai Medical Center, Milwaukee
  • and 9 more
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

RecruitingPhase 3
  • UW Cancer Center at ProHealth Care, Waukesha · 17 mi away
  • ProHealth D N Greenwald Center, Mukwonago · 25 mi away
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06498635

Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

RecruitingPhase 3
  • Froedtert Hospital/Medical College of Wisconsin, Milwaukee
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07222566

This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.

RecruitingPhase 3
  • Aurora St. Luke's Medical Center, Milwaukee
  • Aurora Cancer Care-Grafton, Grafton · 20 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06758401

A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Medical College of Wisconsin, Milwaukee
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06561685

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

RecruitingPhase 1
  • Froedtert Hospital & the Medical College of Wisconsin, Milwaukee
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT06582017

Dosing Physical Activity Among Older Cancer Survivors Who Experience Chronic Pain: a Micro-randomized Trial

Recruiting
  • Froedtert Hospital, Milwaukee
Ages 65 and older · All sexes · Updated Aug 20, 2026 · NCT07227077

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

RecruitingPhase 3
  • Aurora Cancer Care-Milwaukee, Milwaukee
  • Aurora Saint Luke's Medical Center, Milwaukee
  • Medical College of Wisconsin, Milwaukee
  • and 11 more
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05624996

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

RecruitingPhase 2
  • Aurora Cancer Care-Milwaukee, Milwaukee
  • Aurora Saint Luke's Medical Center, Milwaukee
  • Aurora Sinai Medical Center, Milwaukee
  • and 4 more
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT05642572

Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2/3
  • Aurora Cancer Care-Milwaukee, Milwaukee
  • Aurora Saint Luke's Medical Center, Milwaukee
  • Aurora Sinai Medical Center, Milwaukee
  • and 5 more
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT06616584

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

RecruitingObservational study
  • Medical College of Wisconsin, Milwaukee
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT04075305

Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy

Recruiting
  • Clement J. Zablocki VA Medical Center, Milwaukee, WI, Milwaukee
Ages 18 and older · All sexes · Updated Feb 19, 2026 · NCT02984761

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

RecruitingObservational study
  • Aurora Cancer Care-Milwaukee, Milwaukee
  • Ascension Columbia Saint Mary's Hospital - Milwaukee, Milwaukee
  • Aurora Saint Luke's Medical Center, Milwaukee
  • and 11 more
Ages 18 and older · All sexes · Updated Jan 9, 2026 · NCT06073431

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Milwaukee
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

RecruitingObservational study
  • Ascension Columbia St. Mary's Wisconsin, Milwaukee
Ages 50 and older · All sexes · Updated Aug 5, 2025 · NCT06122077

About Lung Cancer

Lung cancer forms in tissues of the lung, usually in the cells that line the air passages. It is the leading cause of cancer death in both men and women.

More about Lung Cancer on MedlinePlus

Lung Cancer trials in other cities

Other studies in Milwaukee

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.