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Prostate Cancer clinical trials in Milwaukee, WI

20 studies for Prostate Cancer are looking for participants at sites in and around Milwaukee (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

RecruitingPhase 3
  • Medical College of Wisconsin ( Site 0020), Milwaukee
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06136650

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

RecruitingPhase 2
  • Aurora Cancer Care-Milwaukee, Milwaukee
  • Aurora Saint Luke's Medical Center, Milwaukee
  • Aurora Sinai Medical Center, Milwaukee
  • and 7 more
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT03866382

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

RecruitingPhase 3
  • Medical College of Wisconsin, Milwaukee
Ages 18 to 100 · Men · Updated Sep 22, 2026 · NCT06855277

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

RecruitingPhase 3
  • Medical College of Wisconsin ( Site 0008), Milwaukee
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT06925737

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

RecruitingPhase 3
  • Aurora Cancer Care-Milwaukee, Milwaukee
  • Aurora Saint Luke's Medical Center, Milwaukee
  • Medical College of Wisconsin, Milwaukee
  • and 8 more
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05946213

Pacritinib in Participants With Metastatic Castrate-Resistant Prostate Cancer That Progressed on or After Prior Treatment With Androgen Receptor Signaling Inhibitors

RecruitingPhase 2
  • Froedtert & the Medical College of Wisconsin, Milwaukee
Ages 18 and older · Men · Updated Sep 9, 2026 · NCT07226713

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Aurora Cancer Care-Milwaukee, Milwaukee
  • Aurora Saint Luke's Medical Center, Milwaukee
  • Aurora Sinai Medical Center, Milwaukee
  • and 6 more
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Zablocki Veterans Administration Medical Center, Milwaukee
Ages 45 to 75 · All sexes · Updated Sep 2, 2026 · NCT06995898

Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

RecruitingPhase 3
  • Medical College of Wisconsin, Milwaukee
  • Drexel Town Square Health Center, Oak Creek · 11 mi away
  • Froedtert and MCW Moorland Reserve Health Center, New Berlin · 11 mi away
  • and 1 more
Ages 18 and older · Men · Updated Sep 2, 2026 · NCT07200830

Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial

RecruitingPhase 3
  • Ascension Columbia Saint Mary's Hospital-Milwaukee Campus, Milwaukee
  • Medical College of Wisconsin, Milwaukee
  • Ascension Southeast Wisconsin Hospital-Mayfair Road-Wauwatosa, Wauwatosa · 5 mi away
  • and 6 more
Ages 18 and older · Men · Updated Sep 2, 2026 · NCT06931340

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

RecruitingPhase 2
  • Medical College of Wisconsin, Milwaukee
  • Drexel Town Square Health Center, Oak Creek · 11 mi away
  • Froedtert Menomonee Falls Hospital, Menomonee Falls · 14 mi away
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06632977

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

RecruitingPhase 1
  • Froedtert Hospital & the Medical College of Wisconsin, Milwaukee
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT06582017

Dosing Physical Activity Among Older Cancer Survivors Who Experience Chronic Pain: a Micro-randomized Trial

Recruiting
  • Froedtert Hospital, Milwaukee
Ages 65 and older · All sexes · Updated Aug 20, 2026 · NCT07227077

Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

RecruitingPhase 1
  • Froedtert Hospital and the Medical College of Wisconsin, Milwaukee
Ages 18 to 100 · Men · Updated Aug 13, 2026 · NCT05519449

Evaluation of Neoadjuvant Xaluritamig in Localized Prostate Cancer

RecruitingPhase 1
  • Medical College of Wisconsin, Milwaukee
Ages 18 and older · Men · Updated Jul 31, 2026 · NCT06613100

Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

RecruitingPhase 2/3
  • Clement J. Zablocki VA Medical Center, Milwaukee, WI, Milwaukee
Ages 18 and older · Men · Updated Apr 8, 2026 · NCT04787744

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

RecruitingObservational study
  • Medical College of Wisconsin, Milwaukee
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT04075305

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Milwaukee
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

RecruitingPhase 3
  • Medical College of Wisconsin, Milwaukee
  • Zablocki Veterans Administration Medical Center, Milwaukee
  • Drexel Town Square Health Center, Oak Creek · 11 mi away
  • and 1 more
Ages 18 and older · Men · Updated Sep 11, 2025 · NCT03678025

About Prostate Cancer

Prostate cancer is one of the most common types of cancer among American men. The risk goes up as men age. Learn about symptoms, tests, and treatment.

More about Prostate Cancer on MedlinePlus

Prostate Cancer trials in other cities

Other studies in Milwaukee

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.