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Esophageal Adenocarcinoma clinical trials in California

22 studies for Esophageal Adenocarcinoma are looking for participants at sites in California.

Cities in California

A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers

  • City of Hope, Duarte
  • Hoag Memorial Hospital Presbyterian, Newport Beach
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07544589

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

  • Kaiser Permanente-Anaheim, Anaheim
  • Kaiser Permanente-Baldwin Park, Baldwin Park
  • Kaiser Permanente-Bellflower, Bellflower
  • and 37 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06203600

mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

  • Kaiser Permanente-Deer Valley Medical Center, Antioch
  • PCR Oncology, Arroyo Grande
  • Sutter Auburn Faith Hospital, Auburn
  • and 61 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05677490

A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

  • City of Hope National Medical Center, Duarte
  • City of Hope at Irvine Lennar, Irvine
  • Ronald Reagan UCLA Medical Center, Los Angeles
  • and 3 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07090499

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)

  • USC/Norris Comprehensive Cancer Center, Los Angeles
  • University of California, Irvine (UCI) Health - UC Irvine Medical Center, Orange
  • Local Institution - 0428, San Francisco
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07221149

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

  • The Oncology Institute of Hope and Innovation, Cerritos
  • Ellison Medical Institute, Los Angeles
  • Valkyrie Clinical Trials, Los Angeles
  • and 3 more
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06324357

Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer

  • UCLA Hematology/Oncology - Atascadero, Atascadero
  • UCLA Hematology/Oncology - Burbank, Burbank
  • UCLA Hematology/Oncology - Encino, Encino
  • and 5 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07392892

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

  • City of Hope Cancer Center-Duarte, Duarte
  • Providence Medical Foundation, Santa Rosa
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07277413

Lucid Registry Study

  • LUCID DX, Lake Forest
RecruitingObservational study
All ages · All sexes · Updated Sep 28, 2026 · NCT05965999

Surveillance vs. Endoscopic Therapy for Barrett's Esophagus With Low-grade Dysplasia

  • University of California, Los Angeles, Los Angeles
  • Kaiser Permanente Oakland Medical Center, Oakland
  • Kaiser Permanente, San Jose
Recruiting
Ages 18 to 89 · All sexes · Updated Sep 11, 2026 · NCT05753748

A Study of KK2269 in Adult Participants With Solid Tumors

  • City Of Hope National Medical Center, Duarte
  • Hoag Memorial Hospital Presbyterian, Newport Beach
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06266299

Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

  • Research Site, Duarte
  • Research Site, Fountain Valley
  • Research Site, Fullerton
  • and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07431281

Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers

  • University of California, San Francisco, San Francisco
  • John Muir Medical Center-Walnut Creek, Walnut Creek
Recruiting
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT04221893

A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)

  • Los Angeles Cancer Network, Los Angeles
  • Pih Health Hematology Medical Oncology, Whittier
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06330064

A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

  • City of Hope, Duarte
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT06657144

ProofPrincip IntraTu TCells SinglDoseImmunCheckpoinInhib Gastro-Esophage Adenocarcinoma w/ARID1a Mu

  • Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange
RecruitingEarly phase 1
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT06824363

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

  • Providence Medical Foundation, Anaheim
  • Providence Medical Foundation, Fullerton
  • Providence St. Jude Medical Center Virginia K Crosson and Infusion Center, Fullerton
  • and 7 more
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT04389632

Seattle Biopsy Protocol Versus Wide-Area Transepithelial Sampling in Patients With Barrett's Esophagus Undergoing Surveillance

  • UCLA / Jonsson Comprehensive Cancer Center, Los Angeles
  • Kaiser Permanente, Oakland
Recruiting
Ages 18 to 89 · All sexes · Updated Jul 1, 2026 · NCT05530343

First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

  • Research Site, Duarte
  • Research Site, Orange
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT07284186

Givastomig Combined With Nivolumab and Chemotherapy in Adults With CLDN18.2 Positive Metastatic Gastric Cancer (GIVA-2)

  • I-MAB Site 1005, Duarte
RecruitingPhase 2
Ages 18 and older · All sexes · Updated May 14, 2026 · NCT07432295

Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors

  • Stern Center for Cancer Clinical Trials and Research, Orange
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT04900818

A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer

  • VA Palo Alto Health Care System, Palo Alto, CA, Palo Alto
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 5, 2025 · NCT05563766

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.