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Head and Neck Squamous Cell Carcinoma clinical trials in Wisconsin

15 studies for Head and Neck Squamous Cell Carcinoma are looking for participants at sites in Wisconsin.

Cities in Wisconsin

High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer

  • Aspirus Cancer Care-Antigo-Volm Cancer Center, Antigo
  • Aurora Cancer Care-Southern Lakes VLCC, Burlington
  • Aurora Saint Luke's South Shore, Cudahy
  • and 27 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06992427

FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

  • Site #0141, Madison
  • Site #0157, Madison
  • Site # 0153, Milwaukee
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06788990

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

  • Exelixis Clinical Site #33, Milwaukee
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

  • Aurora Cancer Care-Southern Lakes VLCC, Burlington
  • Aurora Saint Luke's South Shore, Cudahy
  • Marshfield Medical Center-EC Cancer Center, Eau Claire
  • and 23 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06589804

A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

  • Research Site, Milwaukee
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05877599

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

  • Duluth Clinic Ashland, Ashland
  • Marshfield Medical Center-EC Cancer Center, Eau Claire
  • Saint Vincent Hospital Cancer Center Green Bay, Green Bay
  • and 17 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05136196

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

  • Aspirus Cancer Care-Antigo-Volm Cancer Center, Antigo
  • ThedaCare Regional Cancer Center, Appleton
  • Saint Vincent Hospital Cancer Center Green Bay, Green Bay
  • and 10 more
RecruitingPhase 2
Ages 18 to 79 · All sexes · Updated Sep 22, 2026 · NCT04671667

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

  • Froedtert & MCW Cancer Center, Milwaukee
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07109726

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

  • ThedaCare Regional Cancer Center, Appleton
  • Duluth Clinic Ashland, Ashland
  • Northwest Wisconsin Cancer Center, Ashland
  • and 26 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT02734537

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

  • ThedaCare Regional Cancer Center, Appleton
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)

  • ThedaCare, Appleton
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06163534

Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

  • Froedtert Menomonee Falls Hospital, Menomonee Falls
  • Medical College of Wisconsin, Milwaukee
  • Froedtert and MCW Moorland Reserve Health Center, New Berlin
  • and 2 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT04333537

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

  • Langlade Hospital and Cancer Center, Antigo
  • Northwest Wisconsin Cancer Center, Ashland
  • Froedtert Menomonee Falls Hospital, Menomonee Falls
  • and 8 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06532279

Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Head and Neck Cancer Who Cannot Receive Cisplatin

  • Aspirus Cancer Care-Antigo-Volm Cancer Center, Antigo
  • Froedtert Menomonee Falls Hospital, Menomonee Falls
  • Medical College of Wisconsin, Milwaukee
  • and 7 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07441681

A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

  • Froedtert & the Medical College of Wisconsin, Milwaukee
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 4, 2025 · NCT05902988

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.