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Liver Cancer (Hepatocellular Carcinoma) clinical trials in New York City, NY

24 studies for Liver Cancer (Hepatocellular Carcinoma) are looking for participants at sites in and around New York City (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Study of ZW251 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07164313

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #60, New York
  • Exelixis Clinical Site #6, New York
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

Study of the Theranostic Pair RYZ811 (Diagnostic) and RYZ801 (Therapeutic) to Identify and Treat Subjects With GPC3+ (Glypican-3) Unresectable HCC

RecruitingPhase 1/2
  • Research Facility, New York
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06726161

Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations

RecruitingPhase 1
  • Columbia University Irving Medical Center, New York
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06915753

A Phase 1/2 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Memorial Sloan Kettering Cancer Center Mskcc, New York
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT06427941

Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

RecruitingObservational study
  • NYU Langone Health, New York
  • Columbia University Irving Medical Center, New York
  • Memorial Sloan Kettering Cancer Center, New York
  • and 1 more
Ages 22 and older · All sexes · Updated Sep 11, 2026 · NCT06486454

Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma

RecruitingPhase 3
  • Research Site, New York
  • Research Site, New York
  • Research Site, New York
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06921785

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

RecruitingPhase 1
  • New York Cancer & Blood Specialists, New York
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT06582017

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

RecruitingPhase 1/2
  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial

RecruitingPhase 3
  • Mount Sinai Hospital, New York
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07166406

A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)

RecruitingPhase 1/2
  • NYU Langone Health, New York
  • Icahn School of Medicine At Mount Sinai Prime, New York
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06330064

Atezolizumab and Bevacizumab in Combination With Y^90 Radioembolization in HCC for Liver Transplant

RecruitingPhase 4
  • Icahn School of Medicine at Mount Sinai, New York
Ages 18 and older · All sexes · Updated Jul 28, 2026 · NCT07059494

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

RecruitingPhase 2
  • Columbia University Irving Medical Center, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 8 and older · All sexes · Updated Jul 27, 2026 · NCT05503797

A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma

RecruitingPhase 1
  • Clinical Trial Site, New York
Ages 18 and older · All sexes · Updated Jun 17, 2026 · NCT06600321

Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

Recruiting
  • VA NY Harbor Healthcare System, New York, NY, New York
Ages 18 to 75 · All sexes · Updated Jun 17, 2026 · NCT05486572

A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies

RecruitingPhase 1
  • Memorial Sloan Kettering Cancer Center, New York
Ages 16 and older · All sexes · Updated Jun 2, 2026 · NCT07197554

DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

RecruitingPhase 2
  • USA04-0, New York
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06953089

A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma

RecruitingPhase 1/2
  • Memorial Sloan Kettering Cancer Center - New York, New York
Ages 18 and older · All sexes · Updated Apr 27, 2026 · NCT05440708

HOPE Against Cancer Recurrence in HCC

RecruitingPhase 4
  • Rutgers New Jersey Medical School (New York), New York
Ages 18 and older · All sexes · Updated Dec 16, 2025 · NCT06717919

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

RecruitingPhase 1/2
  • Research Site 107, New York
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, New York
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

The Dragon PLC Trial (DRAGON-PLC)

Recruiting
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated May 15, 2025 · NCT06914648

Liver Cancer (Hepatocellular Carcinoma) trials in other cities

Other studies in New York City

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.