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Metastatic Cancer clinical trials in Madison, WI

21 studies for Metastatic Cancer are looking for participants at sites in and around Madison (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

RecruitingPhase 2
  • University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison
  • University of Wisconsin Carbone Cancer Center - University Hospital, Madison
All ages · All sexes · Updated Oct 2, 2026 · NCT05564377

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • University of Wisconsin Carbone Cancer Center, Madison
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

RecruitingPhase 3
  • University of Wisconsin Carbone Cancer Center, Madison
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07562152

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

RecruitingPhase 1
  • University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison
  • University of Wisconsin Carbone Cancer Center - University Hospital, Madison
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05372614

A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell Carcinoma

RecruitingPhase 1
  • University of Wisconsin - Carbone Cancer Center, Madison
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06234605

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

RecruitingPhase 1
  • Wisconsin Institute for Medical Research, Madison
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06625775

A Study of ASP3082 in Adults With Advanced Solid Tumors

RecruitingPhase 1
  • University of Wisconsin Hospital, Madison
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT05382559

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

RecruitingPhase 3
  • University of Wisconsin Carbone Cancer Center - University Hospital, Madison
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213804

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • SSM Health Dean Medical Group - South Madison Campus Health Research/Circuit Clinical, Madison
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)

RecruitingPhase 2
  • University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison
  • University of Wisconsin Carbone Cancer Center - University Hospital, Madison
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06311214

Biomarkers to Detect Endocrine Therapy Resistance

RecruitingPhase 2
  • UW Carbone Cancer Center, Madison
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT06067503

Y-NM600 in Patients Receiving Anti-PD-1 or Anti-PD-L1 for Metastatic Cancer

RecruitingPhase 1
  • UW Carbone Cancer Center, Madison
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT07197671

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • University of Wisconsin, Carbone Cancer Center, Madison
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes

RecruitingPhase 1
  • University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison
  • University of Wisconsin Carbone Cancer Center - University Hospital, Madison
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT05687110

A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)

RecruitingPhase 1
  • University of Wisconsin, Madison
Ages 18 and older · Men · Updated Jul 9, 2026 · NCT07103018

Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

RecruitingPhase 2/3
  • William S. Middleton Memorial Veterans Hospital, Madison, WI, Madison
Ages 18 and older · Men · Updated Apr 8, 2026 · NCT04787744

A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma

RecruitingPhase 2/3
  • University Of Wisconsin Carbone Cancer Center - University Hospital, Madison
All ages · All sexes · Updated Apr 2, 2026 · NCT06581406

Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • UW Carbone Cancer Center, Madison
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT04900818

IFx-Hu2.0 As An Adjunctive Therapy To Pembrolizumab In Advanced Or Metastatic Merkel Cell Carcinoma (MCC)

RecruitingPhase 1
  • University of Wisconsin Carbone Cancer Center, Madison
Ages 18 and older · All sexes · Updated Oct 15, 2025 · NCT06940440

Comparing Dosing Intervals of Nivolumab or Pembrolizumab in Locally Advanced or Metastatic Cancers

RecruitingPhase 1
  • SSM Health Cancer Care, Madison
Ages 18 and older · All sexes · Updated Oct 1, 2025 · NCT04295863

In Vivo Liquid Biopsy of Melanoma (Cytophone)

RecruitingHealthy volunteers welcome
  • SSM Health Dean Medical Group Specialty Services, Madison
Ages 18 to 80 · All sexes · Updated Mar 11, 2025 · NCT06488365

Metastatic Cancer trials in other cities

Other studies in Madison

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.