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Metastatic Cancer clinical trials recruiting in the U.S.
282 studies for Metastatic Cancer are recruiting participants at sites across the United States.
Cities with the most studies
- Houston, TX104 studies
- New York City, NY93 studies
- Nashville, TN69 studies
- Boston, MA63 studies
- Los Angeles, CA57 studies
- Arlington, VA53 studies
- St. Louis, MO53 studies
- Philadelphia, PA46 studies
- Chicago, IL45 studies
- San Antonio, TX44 studies
- Washington, DC43 studies
- Dallas, TX42 studies
- Seattle, WA39 studies
- Durham, NC33 studies
- Pittsburgh, PA31 studies
- Rochester, MN30 studies
- Baldwin Park, CA30 studies
- Portland, OR30 studies
- Cleveland, OH30 studies
- Tampa, FL29 studies
- San Diego, CA29 studies
- Denver, CO29 studies
- Orlando, FL29 studies
- San Francisco, CA29 studies
- Queens, NY28 studies
- Jacksonville, FL28 studies
- Baltimore, MD28 studies
- Atlanta, GA27 studies
- Columbus, OH26 studies
- Detroit, MI25 studies
- Mountain View, CA25 studies
- Aurora, CO25 studies
- Miami, FL23 studies
- New Haven, CT23 studies
- Grand Rapids, MI22 studies
- Madison, WI21 studies
- Salt Lake City, UT20 studies
- Phoenix, AZ20 studies
- Cincinnati, OH20 studies
- Orange, CA20 studies
By state
- Alabama13 studies
- Arizona45 studies
- Arkansas14 studies
- California129 studies
- Colorado50 studies
- Connecticut27 studies
- Delaware8 studies
- District of Columbia24 studies
- Florida91 studies
- Georgia33 studies
- Hawaii5 studies
- Idaho5 studies
- Illinois58 studies
- Indiana25 studies
- Iowa10 studies
- Kansas15 studies
- Kentucky17 studies
- Louisiana20 studies
- Maine9 studies
- Maryland47 studies
- Massachusetts65 studies
- Michigan52 studies
- Minnesota39 studies
- Mississippi6 studies
- Missouri58 studies
- Montana4 studies
- Nebraska16 studies
- Nevada10 studies
- New Hampshire11 studies
- New Jersey42 studies
- New Mexico13 studies
- New York110 studies
- North Carolina52 studies
- North Dakota5 studies
- Ohio61 studies
- Oklahoma16 studies
- Oregon30 studies
- Pennsylvania68 studies
- Rhode Island9 studies
- South Carolina13 studies
- South Dakota9 studies
- Tennessee74 studies
- Texas139 studies
- Utah31 studies
- Vermont4 studies
- Virginia66 studies
- Washington48 studies
- West Virginia6 studies
- Wisconsin34 studies
Recently updated studies
A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors
RecruitingPhase 1
Ages 19 and older · All sexes · Updated Sep 28, 2026 · NCT06586957A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07277413Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
RecruitingPhase 2
All ages · All sexes · Updated Sep 28, 2026 · NCT05564377A Study of NEOK001, a B7-H3 and ROR1 Targeting Bispecific ADC in Participants With Select Solid Tumors
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07612176A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06989437Parenting Support Intervention for Families Coping With Metastatic or Locally Recurrent Solid Tumor Diagnosis
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05059678A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05)
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06103864Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07222566Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07562152A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations
RecruitingPhase 1/2
Up to age 25 · All sexes · Updated Sep 25, 2026 · NCT04094610ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07007559A Study of KIVU-107 in Participants With Locally Advanced or Metastatic Solid Tumors
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT07229313MTI-301 for the Treatment of Metastatic or Unresectable and Refractory Solid Cancers
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06911008A Phase 1 Study of BPX-601 CAR T-Cell Therapy in Adult Participants With Prostate Cancer That Has Returned, is Resistant to Treatment and Has Spread
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 24, 2026 · NCT07543055A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Sep 24, 2026 · NCT05118789Intratumoral N17350 in Advanced Solid Tumors
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07339176A Study of ZEN003694 in People With Squamous Cell Lung Cancer
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT05607108Pemigatinib + Afatinib in Advanced Refractory Solid Tumors
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06302621Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06915753A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07174336A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07218380A Study of LY4257496 in Participants With Cancer (OMNIRAY)
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07114601SLV-154 Treatment of Advanced Cancers
RecruitingPhase 1
Ages 12 and older · All sexes · Updated Sep 22, 2026 · NCT06771219EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07262619From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.