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Metastatic Cancer clinical trials recruiting in the U.S.
281 studies for Metastatic Cancer are recruiting participants at sites across the United States.
Cities with the most studies
- Houston, TX100 studies
- New York City, NY93 studies
- Nashville, TN69 studies
- Boston, MA61 studies
- Los Angeles, CA57 studies
- Arlington, VA52 studies
- St. Louis, MO52 studies
- San Antonio, TX44 studies
- Washington, DC44 studies
- Dallas, TX44 studies
- Philadelphia, PA42 studies
- Chicago, IL42 studies
- Seattle, WA39 studies
- Durham, NC33 studies
- Pittsburgh, PA31 studies
- Baldwin Park, CA30 studies
- Cleveland, OH30 studies
- Tampa, FL30 studies
- San Diego, CA29 studies
- Atlanta, GA29 studies
- Portland, OR29 studies
- Orlando, FL28 studies
- Rochester, MN28 studies
- Queens, NY28 studies
- Jacksonville, FL27 studies
- Baltimore, MD26 studies
- Columbus, OH25 studies
- San Francisco, CA25 studies
- Denver, CO25 studies
- Mountain View, CA24 studies
- Aurora, CO24 studies
- Miami, FL22 studies
- Detroit, MI22 studies
- New Haven, CT22 studies
- Cincinnati, OH21 studies
- Orange, CA21 studies
- Grand Rapids, MI21 studies
- Edison, NJ20 studies
- Madison, WI20 studies
- Phoenix, AZ19 studies
By state
- Alabama14 studies
- Arizona44 studies
- Arkansas14 studies
- California123 studies
- Colorado48 studies
- Connecticut28 studies
- Delaware9 studies
- District of Columbia26 studies
- Florida86 studies
- Georgia36 studies
- Hawaii6 studies
- Idaho5 studies
- Illinois52 studies
- Indiana23 studies
- Iowa10 studies
- Kansas14 studies
- Kentucky16 studies
- Louisiana18 studies
- Maine9 studies
- Maryland44 studies
- Massachusetts63 studies
- Michigan48 studies
- Minnesota37 studies
- Mississippi6 studies
- Missouri57 studies
- Montana4 studies
- Nebraska16 studies
- Nevada11 studies
- New Hampshire11 studies
- New Jersey42 studies
- New Mexico13 studies
- New York108 studies
- North Carolina52 studies
- North Dakota5 studies
- Ohio59 studies
- Oklahoma18 studies
- Oregon29 studies
- Pennsylvania65 studies
- Rhode Island9 studies
- South Carolina14 studies
- South Dakota9 studies
- Tennessee74 studies
- Texas137 studies
- Utah27 studies
- Vermont4 studies
- Virginia64 studies
- Washington49 studies
- West Virginia6 studies
- Wisconsin32 studies
Recently updated studies
A Study to Assess Safety and Efficacy of SOT109 in Patients With Advanced Unresectable or Metastatic Colorectal Cancer
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT07693751CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT07335497Durvalumab in Combination With Chemotherapy in Treating Patients With Advanced Solid Tumors, DURVA+ Trial
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT03907475Preoperative Y-90 Radioembolization for Tumor Control and Future Liver Remnant Hypertrophy in Patients With Colorectal Liver Metastases
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT05195710Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes
Recruiting
Ages 18 to 99 · All sexes · Updated Nov 12, 2026 · NCT04907643Testing the Combination of the Anticancer Drugs ZEN003694 and Binimetinib in Patients With Advanced/Metastatic or Unresectable Solid Tumors With RAS Alterations and Triple Negative Breast Cancer
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT05111561The Role of 68-Gallium-DOTATATE-PET/CT in the Imaging of Metastatic Thyroid Cancer
RecruitingPhase 2
Ages 18 to 98 · All sexes · Updated Nov 12, 2026 · NCT04927416A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06270706Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors
RecruitingPhase 1
Ages 12 and older · All sexes · Updated Nov 12, 2026 · NCT05372640Testing the Combination of DS-8201a and Olaparib in HER2-Expressing Cancers With Expansion in Patients With Platinum Resistant Ovarian Cancer
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT04585958A Phase 1 Dose Escalation and Dose Expansion Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07458347Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
RecruitingPhase 2
All ages · All sexes · Updated Nov 12, 2026 · NCT05564377Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT05372614Beamion LUNG-1: A Study to Test Different Doses of Zongertinib in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene)
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT04886804BL-M07D1 (Trastuzumab Brengitecan T-bren) vs Standard of Care Platinum-based Chemotherapy (PBC) for HER2-expressing Metastatic Urothelial Cancer After Progression on Anti-PD-(L)1-based Therapy
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT07869836A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT07020221LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 10, 2026 · NCT06216301Highly Selective CDK7 Inhibitor Q901 in Selected Advanced Solid Tumors
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT05394103ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT07007559Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT07562152A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Nov 6, 2026 · NCT05384626CREO - Microwave Ablation Feasibility Study
Recruiting
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT07817147A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors
RecruitingPhase 1
Ages 18 to 99 · All sexes · Updated Nov 6, 2026 · NCT06983743Modified FOLFIRINOX and Pentamidine in Advanced and Metastatic Pancreatic Cancer
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT07829185Multiple Dose Intraventricular Administration of Rhenium-186 NanoLiposome for Leptomeningeal Metastases
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07098806From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.