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Treatment-Resistant Depressive Disorder clinical trials in Missouri
7 studies for Treatment-Resistant Depressive Disorder are looking for participants at sites in Missouri.
Cities in Missouri
Lumateperone for Late-Life Depression
- Washington University School of Medicine, St Louis
RecruitingPhase 3
Ages 60 and older · All sexes · Updated Sep 16, 2026 · NCT07623135ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response
- St. Charles Psychiatric Associates, Inc. dba Midwest Research Group, Saint Charles
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Sep 14, 2026 · NCT07284667Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
- Washington University School of Medicine, St Louis
Recruiting
Ages 22 to 70 · All sexes · Updated Aug 28, 2026 · NCT06423430A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
- University of Missouri, Columbia
- Psychiatric Care and Research, O'Fallon
- Washington University School of Medicine, St Louis
Recruiting
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT03887715A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
- Midwest Research Group, Saint Charles
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated May 11, 2026 · NCT06524830NMDA Receptor Antagonist Nitrous Oxide Targets Affective Brain Circuits
- Washington University School of Medicine, St Louis
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Apr 29, 2026 · NCT02994433Disruptions of Brain Networks and Sleep by Electroconvulsive Therapy
- Washington University School of Medicine/Barnes-Jewish Hospital, St Louis
RecruitingObservational study
Ages 21 to 65 · All sexes · Updated Mar 12, 2026 · NCT05905705From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.